Add-on imeglimin versus metformin dose escalation regarding glycemic control in patients with type 2 diabetes treated with a dipeptidyl peptidase-4 inhibitor plus low-dose metformin: study protocol for a multicenter, prospective, randomized, open-label, parallel-group comparison study (MEGMI study)
Introduction Imeglimin is a novel anti-hyperglycemic drug that improves both insulin resistance and insulin secretion. The effects of imeglimin on glycemic control were confirmed in phase III clinical trials, but little is known about its effectiveness in daily clinical practice settings, especially...
Main Authors: | Kyu Yong Cho, Tatsuya Atsumi, Hiroshi Nomoto, Jun Takeuchi, So Nagai, Akinobu Nakamura, Hideaki Miyoshi, Shinji Taneda, Aika Miya, Hiraku Kameda, Akihiro Takahashi, Hiroyoshi Kurihara |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2022-12-01
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Series: | BMJ Open Diabetes Research & Care |
Online Access: | https://drc.bmj.com/content/10/6/e002988.full |
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