Selective Suppression of Integrin‐Ligand Binding by Single Molecular Tension Probes Mediates Directional Cell Migration

Selective Suppression of Integrin‐Ligand Binding by Single Molecular Tension Probes Mediates Directional Cell Migration

Abstract Cell migration interacting with continuously changing microenvironment, is one of the most essential cellular functions, participating in embryonic development, wound repair, immune response, and cancer metastasis. The migration process is finely tuned by integrin‐mediated binding to ligand...

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Bibliographic Details
Main Authors: Seong‐Beom Han, Geonhui Lee, Daesan Kim, Jeong‐Ki Kim, In‐San Kim, Hae‐Won Kim, Dong‐Hwee Kim
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Advanced Science
Subjects:
cell adhesion
FAK phosphorylation
integrin αvβ3
molecular tension probes
persistent migration
Online Access:https://doi.org/10.1002/advs.202306497

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