A Compartmental Model to Investigate Local and Global Ca2+ Dynamics in Astrocytes

A Compartmental Model to Investigate Local and Global Ca2+ Dynamics in Astrocytes

Intracellular Ca2+ dynamics in astrocytes can be triggered by neuronal activity and in turn regulate a variety of downstream processes that modulate neuronal function. In this fashion, astrocytic Ca2+ signaling is regarded as a processor of neural network activity by means of complex spatial and tem...

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Bibliographic Details
Main Authors: Evan Cresswell-Clay, Nathan Crock, Joël Tabak, Gordon Erlebacher
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Computational Neuroscience
Subjects:
calcium spike
spatiotemporal dynamics
diffusion
IP3 receptor
endoplasmic reticulum
glia
Online Access:https://www.frontiersin.org/article/10.3389/fncom.2018.00094/full

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