Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from <i>Cistus ladanifer</i> L.
<i>Cistus ladanifer</i> L. is a plant widely used in folk medicine to treat various illnesses. This study aims to evaluate the effect of the plant flourishing time harvest on the chemical composition and the antimicrobial effect of its essential oil. Chemical analysis of the essential oi...
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MDPI AG
2021-09-01
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| author | Jamila El Karkouri Mohamed Bouhrim Omkulthom Mohamed Al Kamaly Hamza Mechchate Amal Kchibale Imad Adadi Sanae Amine Souâd Alaoui Ismaili Touriya Zair |
| author_facet | Jamila El Karkouri Mohamed Bouhrim Omkulthom Mohamed Al Kamaly Hamza Mechchate Amal Kchibale Imad Adadi Sanae Amine Souâd Alaoui Ismaili Touriya Zair |
| author_sort | Jamila El Karkouri |
| collection | DOAJ |
| description | <i>Cistus ladanifer</i> L. is a plant widely used in folk medicine to treat various illnesses. This study aims to evaluate the effect of the plant flourishing time harvest on the chemical composition and the antimicrobial effect of its essential oil. Chemical analysis of the essential oil was carried out using gas chromatography-mass spectrometry (GC-MS). The antibacterial and antifungal proprieties were tested against four selected bacteria (<i>Staphylococcus aureus</i>, <i>Salmonella Typhi</i>, <i>Escherichia coli</i>, and <i>Acinetobacter baumannii</i>) and nine fungi (Yeasts (<i>Candida tropicalis</i>, <i>Candida glabrata</i>, <i>Candida dubliniensis</i>, <i>Candida</i> sp., <i>Rhodotorula rubra</i>, <i>Cryptococcus neoformans</i>) and molds (<i>Penicillium</i> sp. (P), <i>Fusarium</i> sp. (F), <i>Aspergillus niger</i> (<i>A. niger</i>)), respectively. The essential oil of <i>C. ladanifer</i> demonstrated a powerful antibacterial activity with an inhibition zone of 55 ± 0.22 mm <i>for Staphylococcus aureus,</i> 42 ± 0.11 mm for <i>Escherichia coli,</i> 35 ± 0.27 mm for <i>Acinetobacter baumannii (Full resistant to antibiotics)</i> and 30 ± 0.25 mm for <i>Salmonella Typhi.</i> It also inhibited all tested bacteria at 10 µL/mL. For the antifungal activity test, <i>C. tropicalis</i> and <i>C. neoformans</i> appeared to be the most sensitive strains to the essential oil with an inhibition zone of 13 mm, followed by <i>R. rubra</i> and <i>Penicillium</i> sp. (12 mm), then <i>C. dubliniensis</i> and <i>C. glabrata</i> (11 mm). The chemical analysis of the essential oil by GC-MS revealed that the major components of the essential oil were viridiflorol (17.64%), pinocarveol (11.02%), bornylacetate (9.38%), and ledol (8.85%). <i>C. ladanifer</i> exhibited a remarkable antimicrobial activity that could be more exploited to develop targeted natural remedies against specific diseases. |
| first_indexed | 2024-03-10T06:15:25Z |
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| spelling | doaj.art-97cbfa172b2f4603b4ca925228e6e21a2023-11-22T19:43:17ZengMDPI AGPlants2223-77472021-09-011010206810.3390/plants10102068Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from <i>Cistus ladanifer</i> L.Jamila El Karkouri0Mohamed Bouhrim1Omkulthom Mohamed Al Kamaly2Hamza Mechchate3Amal Kchibale4Imad Adadi5Sanae Amine6Souâd Alaoui Ismaili7Touriya Zair8Research Team of Chemistry Bioactive Molecules and the Environment, Laboratoire des Matériaux Innovants et Biothenologie des Ressources Naturelles, Faculty of Sciences, University Moulay Ismaïl of Meknes, BP 11201, Zitoune, Meknes 50003, MoroccoResearch Team of Chemistry Bioactive Molecules and the Environment, Laboratoire des Matériaux Innovants et Biothenologie des Ressources Naturelles, Faculty of Sciences, University Moulay Ismaïl of Meknes, BP 11201, Zitoune, Meknes 50003, MoroccoDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh 11564, Saudi ArabiaLaboratory of Biotechnology, Environment, Agri-Food, and Health, Faculty of Sciences Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, P.O. Box 1796, Fez 30000, MoroccoResearch Team of Chemistry Bioactive Molecules and the Environment, Laboratoire des Matériaux Innovants et Biothenologie des Ressources Naturelles, Faculty of Sciences, University Moulay Ismaïl of Meknes, BP 11201, Zitoune, Meknes 50003, MoroccoResearch Team of Chemistry Bioactive Molecules and the Environment, Laboratoire des Matériaux Innovants et Biothenologie des Ressources Naturelles, Faculty of Sciences, University Moulay Ismaïl of Meknes, BP 11201, Zitoune, Meknes 50003, MoroccoResearch Team of Chemistry Bioactive Molecules and the Environment, Laboratoire des Matériaux Innovants et Biothenologie des Ressources Naturelles, Faculty of Sciences, University Moulay Ismaïl of Meknes, BP 11201, Zitoune, Meknes 50003, MoroccoResearch Team of Chemistry Bioactive Molecules and the Environment, Laboratoire des Matériaux Innovants et Biothenologie des Ressources Naturelles, Faculty of Sciences, University Moulay Ismaïl of Meknes, BP 11201, Zitoune, Meknes 50003, MoroccoResearch Team of Chemistry Bioactive Molecules and the Environment, Laboratoire des Matériaux Innovants et Biothenologie des Ressources Naturelles, Faculty of Sciences, University Moulay Ismaïl of Meknes, BP 11201, Zitoune, Meknes 50003, Morocco<i>Cistus ladanifer</i> L. is a plant widely used in folk medicine to treat various illnesses. This study aims to evaluate the effect of the plant flourishing time harvest on the chemical composition and the antimicrobial effect of its essential oil. Chemical analysis of the essential oil was carried out using gas chromatography-mass spectrometry (GC-MS). The antibacterial and antifungal proprieties were tested against four selected bacteria (<i>Staphylococcus aureus</i>, <i>Salmonella Typhi</i>, <i>Escherichia coli</i>, and <i>Acinetobacter baumannii</i>) and nine fungi (Yeasts (<i>Candida tropicalis</i>, <i>Candida glabrata</i>, <i>Candida dubliniensis</i>, <i>Candida</i> sp., <i>Rhodotorula rubra</i>, <i>Cryptococcus neoformans</i>) and molds (<i>Penicillium</i> sp. (P), <i>Fusarium</i> sp. (F), <i>Aspergillus niger</i> (<i>A. niger</i>)), respectively. The essential oil of <i>C. ladanifer</i> demonstrated a powerful antibacterial activity with an inhibition zone of 55 ± 0.22 mm <i>for Staphylococcus aureus,</i> 42 ± 0.11 mm for <i>Escherichia coli,</i> 35 ± 0.27 mm for <i>Acinetobacter baumannii (Full resistant to antibiotics)</i> and 30 ± 0.25 mm for <i>Salmonella Typhi.</i> It also inhibited all tested bacteria at 10 µL/mL. For the antifungal activity test, <i>C. tropicalis</i> and <i>C. neoformans</i> appeared to be the most sensitive strains to the essential oil with an inhibition zone of 13 mm, followed by <i>R. rubra</i> and <i>Penicillium</i> sp. (12 mm), then <i>C. dubliniensis</i> and <i>C. glabrata</i> (11 mm). The chemical analysis of the essential oil by GC-MS revealed that the major components of the essential oil were viridiflorol (17.64%), pinocarveol (11.02%), bornylacetate (9.38%), and ledol (8.85%). <i>C. ladanifer</i> exhibited a remarkable antimicrobial activity that could be more exploited to develop targeted natural remedies against specific diseases.https://www.mdpi.com/2223-7747/10/10/2068<i>C. ladanifer</i> var. <i>maculatus</i> Dunessential oilantimicrobial activityyeastmoldchemical analysis |
| spellingShingle | Jamila El Karkouri Mohamed Bouhrim Omkulthom Mohamed Al Kamaly Hamza Mechchate Amal Kchibale Imad Adadi Sanae Amine Souâd Alaoui Ismaili Touriya Zair Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from <i>Cistus ladanifer</i> L. Plants <i>C. ladanifer</i> var. <i>maculatus</i> Dun essential oil antimicrobial activity yeast mold chemical analysis |
| title | Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from <i>Cistus ladanifer</i> L. |
| title_full | Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from <i>Cistus ladanifer</i> L. |
| title_fullStr | Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from <i>Cistus ladanifer</i> L. |
| title_full_unstemmed | Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from <i>Cistus ladanifer</i> L. |
| title_short | Chemical Composition, Antibacterial and Antifungal Activity of the Essential Oil from <i>Cistus ladanifer</i> L. |
| title_sort | chemical composition antibacterial and antifungal activity of the essential oil from i cistus ladanifer i l |
| topic | <i>C. ladanifer</i> var. <i>maculatus</i> Dun essential oil antimicrobial activity yeast mold chemical analysis |
| url | https://www.mdpi.com/2223-7747/10/10/2068 |
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