Value of Calcium and Phosphorous in chronic kidney disease patients under hemodialysis: A retrospective study
<p><strong>Background: </strong><span style="font-family: Calibri;">Derangements of mineral metabolism occur during early stages of chronic kidney disease (CKD). Mineral metabolism has emerged as important predictors of morbidity and mortality in dialysis patients....
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| Format: | Article |
| Language: | English |
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Association of Clinical Pathologists of Nepal
2012-09-01
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| Series: | Journal of Pathology of Nepal |
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| Online Access: | http://www.nepjol.info/index.php/JPN/article/view/6881 |
| _version_ | 1818297497563430912 |
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| author | S Singh K Upadhyay-Dhungel G Aryal |
| author_facet | S Singh K Upadhyay-Dhungel G Aryal |
| author_sort | S Singh |
| collection | DOAJ |
| description | <p><strong>Background: </strong><span style="font-family: Calibri;">Derangements of mineral metabolism occur during early stages of chronic kidney disease (CKD). Mineral metabolism has emerged as important predictors of morbidity and mortality in dialysis patients. This study aims to evaluate the values of calcium and phosphorous in reference to practice guidelines issued by National Kidney Foundation Dialysis Outcomes Quality Initiative (K/DOQI) in patients undergoing hemodialysis in KIST Medical College Teaching Hospital.</span></p><p><strong>Materials and Methods: </strong><span style="font-family: Calibri;">It was a retrospective study which included 101 patients who underwent hemodialysis in KIST Medical College Teaching Hospital over a period of three months (October 2010 to December 2010). The laboratory parameters of serum calcium, and phosphorus were evaluated and were compared with that of recommended values by K/DOQI guidelines.</span></p><p><strong>Results: </strong><span style="font-family: Calibri;">The mean values for serum calcium, phosphorus, and calcium-phosphorus product were 8.79 ± 1.48 mg/dL, 5.30 ± 1.32 mg/dL and 46.62 ± 1.96 mg2/dL2 respectively. Forty (40%), 53 (53%) and 76 (76%) cases of CKD patients met K/DOQI target value for calcium, phosphorous and calciumphosphorous product respectively. Twenty one percent of the patients meet the three K/DOQI guidelines and 14% did not meet any of the recommended guidelines by K/DOQI.</span></p><p><strong>Conclusion: </strong><span style="font-family: Calibri;">To achieve all the K/DOQI guidelines multi-disciplinary team approach is crucial. More extensive multicenter studies need to be carried out. It is necessary to develop our national guidelines in future.</span></p><p><span style="font-family: Calibri;">Journal of Pathology of Nepal (2012) Vol. 2, 293-296</span></p><p><span style="font-family: Calibri;">DOI: <a href="http://dx.doi.org/10.3126/jpn.v2i4.6881">http://dx.doi.org/10.3126/jpn.v2i4.6881</a></span></p> |
| first_indexed | 2024-12-13T04:20:22Z |
| format | Article |
| id | doaj.art-97cf33e2eda74945b759d9486441a7cb |
| institution | Directory Open Access Journal |
| issn | 2091-0797 2091-0908 |
| language | English |
| last_indexed | 2024-12-13T04:20:22Z |
| publishDate | 2012-09-01 |
| publisher | Association of Clinical Pathologists of Nepal |
| record_format | Article |
| series | Journal of Pathology of Nepal |
| spelling | doaj.art-97cf33e2eda74945b759d9486441a7cb2022-12-21T23:59:46ZengAssociation of Clinical Pathologists of NepalJournal of Pathology of Nepal2091-07972091-09082012-09-012429329610.3126/jpn.v2i4.68815483Value of Calcium and Phosphorous in chronic kidney disease patients under hemodialysis: A retrospective studyS Singh0K Upadhyay-Dhungel1G Aryal2Department of Biochemistry, KIST Medical College, LalitpurDepartment of Physiology, KIST Medical College, LalitpurDepartment of Pathology, KIST Medical College, Lalitpur<p><strong>Background: </strong><span style="font-family: Calibri;">Derangements of mineral metabolism occur during early stages of chronic kidney disease (CKD). Mineral metabolism has emerged as important predictors of morbidity and mortality in dialysis patients. This study aims to evaluate the values of calcium and phosphorous in reference to practice guidelines issued by National Kidney Foundation Dialysis Outcomes Quality Initiative (K/DOQI) in patients undergoing hemodialysis in KIST Medical College Teaching Hospital.</span></p><p><strong>Materials and Methods: </strong><span style="font-family: Calibri;">It was a retrospective study which included 101 patients who underwent hemodialysis in KIST Medical College Teaching Hospital over a period of three months (October 2010 to December 2010). The laboratory parameters of serum calcium, and phosphorus were evaluated and were compared with that of recommended values by K/DOQI guidelines.</span></p><p><strong>Results: </strong><span style="font-family: Calibri;">The mean values for serum calcium, phosphorus, and calcium-phosphorus product were 8.79 ± 1.48 mg/dL, 5.30 ± 1.32 mg/dL and 46.62 ± 1.96 mg2/dL2 respectively. Forty (40%), 53 (53%) and 76 (76%) cases of CKD patients met K/DOQI target value for calcium, phosphorous and calciumphosphorous product respectively. Twenty one percent of the patients meet the three K/DOQI guidelines and 14% did not meet any of the recommended guidelines by K/DOQI.</span></p><p><strong>Conclusion: </strong><span style="font-family: Calibri;">To achieve all the K/DOQI guidelines multi-disciplinary team approach is crucial. More extensive multicenter studies need to be carried out. It is necessary to develop our national guidelines in future.</span></p><p><span style="font-family: Calibri;">Journal of Pathology of Nepal (2012) Vol. 2, 293-296</span></p><p><span style="font-family: Calibri;">DOI: <a href="http://dx.doi.org/10.3126/jpn.v2i4.6881">http://dx.doi.org/10.3126/jpn.v2i4.6881</a></span></p>http://www.nepjol.info/index.php/JPN/article/view/6881CalciumHemodialysisK/DOQIPhosphorus |
| spellingShingle | S Singh K Upadhyay-Dhungel G Aryal Value of Calcium and Phosphorous in chronic kidney disease patients under hemodialysis: A retrospective study Journal of Pathology of Nepal Calcium Hemodialysis K/DOQI Phosphorus |
| title | Value of Calcium and Phosphorous in chronic kidney disease patients under hemodialysis: A retrospective study |
| title_full | Value of Calcium and Phosphorous in chronic kidney disease patients under hemodialysis: A retrospective study |
| title_fullStr | Value of Calcium and Phosphorous in chronic kidney disease patients under hemodialysis: A retrospective study |
| title_full_unstemmed | Value of Calcium and Phosphorous in chronic kidney disease patients under hemodialysis: A retrospective study |
| title_short | Value of Calcium and Phosphorous in chronic kidney disease patients under hemodialysis: A retrospective study |
| title_sort | value of calcium and phosphorous in chronic kidney disease patients under hemodialysis a retrospective study |
| topic | Calcium Hemodialysis K/DOQI Phosphorus |
| url | http://www.nepjol.info/index.php/JPN/article/view/6881 |
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