Application of 3D bioprinting in the prevention and the therapy for human diseases
Abstract Rapid development of vaccines and therapeutics is necessary to tackle the emergence of new pathogens and infectious diseases. To speed up the drug discovery process, the conventional development pipeline can be retooled by introducing advanced in vitro models as alternatives to conventional...
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Format: | Article |
Language: | English |
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Nature Publishing Group
2021-05-01
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Series: | Signal Transduction and Targeted Therapy |
Online Access: | https://doi.org/10.1038/s41392-021-00566-8 |
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author | Hee-Gyeong Yi Hyeonji Kim Junyoung Kwon Yeong-Jin Choi Jinah Jang Dong-Woo Cho |
author_facet | Hee-Gyeong Yi Hyeonji Kim Junyoung Kwon Yeong-Jin Choi Jinah Jang Dong-Woo Cho |
author_sort | Hee-Gyeong Yi |
collection | DOAJ |
description | Abstract Rapid development of vaccines and therapeutics is necessary to tackle the emergence of new pathogens and infectious diseases. To speed up the drug discovery process, the conventional development pipeline can be retooled by introducing advanced in vitro models as alternatives to conventional infectious disease models and by employing advanced technology for the production of medicine and cell/drug delivery systems. In this regard, layer-by-layer construction with a 3D bioprinting system or other technologies provides a beneficial method for developing highly biomimetic and reliable in vitro models for infectious disease research. In addition, the high flexibility and versatility of 3D bioprinting offer advantages in the effective production of vaccines, therapeutics, and relevant delivery systems. Herein, we discuss the potential of 3D bioprinting technologies for the control of infectious diseases. We also suggest that 3D bioprinting in infectious disease research and drug development could be a significant platform technology for the rapid and automated production of tissue/organ models and medicines in the near future. |
first_indexed | 2024-12-16T23:14:55Z |
format | Article |
id | doaj.art-97d3446279db45859a331b482e80975d |
institution | Directory Open Access Journal |
issn | 2059-3635 |
language | English |
last_indexed | 2024-12-16T23:14:55Z |
publishDate | 2021-05-01 |
publisher | Nature Publishing Group |
record_format | Article |
series | Signal Transduction and Targeted Therapy |
spelling | doaj.art-97d3446279db45859a331b482e80975d2022-12-21T22:12:20ZengNature Publishing GroupSignal Transduction and Targeted Therapy2059-36352021-05-016111710.1038/s41392-021-00566-8Application of 3D bioprinting in the prevention and the therapy for human diseasesHee-Gyeong Yi0Hyeonji Kim1Junyoung Kwon2Yeong-Jin Choi3Jinah Jang4Dong-Woo Cho5Department of Rural and Biosystems Engineering, College of Agriculture and Life Sciences, Chonnam National UniversityDepartment of Mechanical Engineering, Pohang University of Science and Technology (POSTECH)Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH)Department of Advanced Biomaterials Research, Korea Institute of Materials Science (KIMS)Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH)Department of Mechanical Engineering, Pohang University of Science and Technology (POSTECH)Abstract Rapid development of vaccines and therapeutics is necessary to tackle the emergence of new pathogens and infectious diseases. To speed up the drug discovery process, the conventional development pipeline can be retooled by introducing advanced in vitro models as alternatives to conventional infectious disease models and by employing advanced technology for the production of medicine and cell/drug delivery systems. In this regard, layer-by-layer construction with a 3D bioprinting system or other technologies provides a beneficial method for developing highly biomimetic and reliable in vitro models for infectious disease research. In addition, the high flexibility and versatility of 3D bioprinting offer advantages in the effective production of vaccines, therapeutics, and relevant delivery systems. Herein, we discuss the potential of 3D bioprinting technologies for the control of infectious diseases. We also suggest that 3D bioprinting in infectious disease research and drug development could be a significant platform technology for the rapid and automated production of tissue/organ models and medicines in the near future.https://doi.org/10.1038/s41392-021-00566-8 |
spellingShingle | Hee-Gyeong Yi Hyeonji Kim Junyoung Kwon Yeong-Jin Choi Jinah Jang Dong-Woo Cho Application of 3D bioprinting in the prevention and the therapy for human diseases Signal Transduction and Targeted Therapy |
title | Application of 3D bioprinting in the prevention and the therapy for human diseases |
title_full | Application of 3D bioprinting in the prevention and the therapy for human diseases |
title_fullStr | Application of 3D bioprinting in the prevention and the therapy for human diseases |
title_full_unstemmed | Application of 3D bioprinting in the prevention and the therapy for human diseases |
title_short | Application of 3D bioprinting in the prevention and the therapy for human diseases |
title_sort | application of 3d bioprinting in the prevention and the therapy for human diseases |
url | https://doi.org/10.1038/s41392-021-00566-8 |
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