Adhesion Molecules and Vulnerable Plaques – Promoters of Acute Coronary Syndromes
Biological factors that characterize extrinsic plaque vulnerability include various pro- and anti-inflammatory cytokines that contribute to the development and progression of atherosclerosis. Adhesion molecules are among the initiators of the atherosclerotic process, by mediation of endothelial infl...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Sciendo
2022-09-01
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| Series: | Journal of Cardiovascular Emergencies |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/jce-2022-0009 |
| _version_ | 1811171380365885440 |
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| author | Opincariu Diana Benedek Theodora |
| author_facet | Opincariu Diana Benedek Theodora |
| author_sort | Opincariu Diana |
| collection | DOAJ |
| description | Biological factors that characterize extrinsic plaque vulnerability include various pro- and anti-inflammatory cytokines that contribute to the development and progression of atherosclerosis. Adhesion molecules are among the initiators of the atherosclerotic process, by mediation of endothelial inflammation. The soluble forms of these adhesion molecules have been identified in the circulatory blood, with an increased level in case of subjects with atherosclerotic lesions and higher levels in patients with acute coronary syndromes or vulnerable plaques. In addition, several authors have found a significant predictive capacity of these molecules in case of patients presenting with acute coronary and cerebrovascular events. The aim of this manuscript is to provide a short description of the role of adhesion molecules in the development and progression of atherosclerotic lesions towards acute coronary syndromes, as well as their capacity for predicting major adverse cardiovascular events in vulnerable cardiovascular patients. |
| first_indexed | 2024-04-10T17:14:07Z |
| format | Article |
| id | doaj.art-97d6ef94944b4067bd77c515dd8cde4f |
| institution | Directory Open Access Journal |
| issn | 2457-5518 |
| language | English |
| last_indexed | 2024-04-10T17:14:07Z |
| publishDate | 2022-09-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Journal of Cardiovascular Emergencies |
| spelling | doaj.art-97d6ef94944b4067bd77c515dd8cde4f2023-02-05T19:15:11ZengSciendoJournal of Cardiovascular Emergencies2457-55182022-09-0183596310.2478/jce-2022-0009Adhesion Molecules and Vulnerable Plaques – Promoters of Acute Coronary SyndromesOpincariu Diana0Benedek Theodora1“George Emil Palade” University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, Romania“George Emil Palade” University of Medicine, Pharmacy, Science and Technology, Târgu Mureș, RomaniaBiological factors that characterize extrinsic plaque vulnerability include various pro- and anti-inflammatory cytokines that contribute to the development and progression of atherosclerosis. Adhesion molecules are among the initiators of the atherosclerotic process, by mediation of endothelial inflammation. The soluble forms of these adhesion molecules have been identified in the circulatory blood, with an increased level in case of subjects with atherosclerotic lesions and higher levels in patients with acute coronary syndromes or vulnerable plaques. In addition, several authors have found a significant predictive capacity of these molecules in case of patients presenting with acute coronary and cerebrovascular events. The aim of this manuscript is to provide a short description of the role of adhesion molecules in the development and progression of atherosclerotic lesions towards acute coronary syndromes, as well as their capacity for predicting major adverse cardiovascular events in vulnerable cardiovascular patients.https://doi.org/10.2478/jce-2022-0009adhesion moleculesendothelial inflammationvulnerable plaquesmajor adverse cardiovascular events |
| spellingShingle | Opincariu Diana Benedek Theodora Adhesion Molecules and Vulnerable Plaques – Promoters of Acute Coronary Syndromes Journal of Cardiovascular Emergencies adhesion molecules endothelial inflammation vulnerable plaques major adverse cardiovascular events |
| title | Adhesion Molecules and Vulnerable Plaques – Promoters of Acute Coronary Syndromes |
| title_full | Adhesion Molecules and Vulnerable Plaques – Promoters of Acute Coronary Syndromes |
| title_fullStr | Adhesion Molecules and Vulnerable Plaques – Promoters of Acute Coronary Syndromes |
| title_full_unstemmed | Adhesion Molecules and Vulnerable Plaques – Promoters of Acute Coronary Syndromes |
| title_short | Adhesion Molecules and Vulnerable Plaques – Promoters of Acute Coronary Syndromes |
| title_sort | adhesion molecules and vulnerable plaques promoters of acute coronary syndromes |
| topic | adhesion molecules endothelial inflammation vulnerable plaques major adverse cardiovascular events |
| url | https://doi.org/10.2478/jce-2022-0009 |
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