{(1R,3S)-2-Benzyl-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinolin-3-yl}diphenylmethanol

{(1R,3S)-2-Benzyl-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinolin-3-yl}diphenylmethanol

In the title compound, C37H35NO3, a precursor to novel chiral catalysts, the N-containing six-membered ring assumes a half-chair conformation. Intermolecular C&#8212;H...O hydrogen bonds link the molecules in the crystal structure.

Bibliographic Details
Main Authors:	Glenn E.M. Maguire, Hendrik G. Kruger, Thavendran Govender, Tricia Naicker
Format:	Article
Language:	English
Published:	International Union of Crystallography 2010-03-01
Series:	Acta Crystallographica Section E
Online Access:	http://scripts.iucr.org/cgi-bin/paper?S1600536810005295

Similar Items

(1S,3S)-Methyl 2-benzyl-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
by: Tricia Naicker, et al.
Published: (2011-06-01)

(1R,3S)-Methyl 2-benzyl-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
by: Glenn E. M. Maguire, et al.
Published: (2009-12-01)

(1R,3S)-N-Benzhydryl-2-benzyl-6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline-3-carbothioamide
by: Tricia Naicker, et al.
Published: (2011-12-01)

(1R,3S)-Methyl 6,7-dimethoxy-1-(4-methoxyphenyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylate
by: Glenn E. M. Maguire, et al.
Published: (2010-12-01)

(S)-N-Benzyl-2-methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
by: Glenn. E.M. Maguire, et al.
Published: (2011-01-01)

(S)-Benzyl 3-phenylcarbamoyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate
by: Glenn E. M. Maguire, et al.
Published: (2012-03-01)

(S)-4-Phenyl-2-(1,2,3,4-tetrahydroisoquinolin-3-yl)-1,3-thiazole
by: Sunayna Pawar, et al.
Published: (2012-01-01)

Crystal structure of 3-(benzhydrylcarbamoyl)-2-benzyl-6,7-dimethoxy-1- phenyl-1,2,3,4-tetrahydroisoquinoline 2-oxide, C38H36N2O4
by: Francis Vivian, et al.
Published: (2014-12-01)

(3S)-2-Benzyl-3-carboxy-1,2,3,4-tetrahydroisoquinolinium chloride monohydrate
by: Glenn E. M. Maguire, et al.
Published: (2011-01-01)

Crystal structure of (S)-N-benzyl-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, C17H20N2O2
by: Cele Zamani E. D., et al.
Published: (2013-10-01)

Diastereoselective Synthesis of (–)-6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic Acid via Morpholinone Derivatives
by: Maria Chrzanowska, et al.
Published: (2023-04-01)

ENANTIOSPECIFIC SYNTHESIS OF (+)-(R)-6,7-DIMETHOXY-2-METHYL-4-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLINE FROM (+)-(S)-2-METHYLAMINO-1-PHENYLETHANOL (HALOSTACHINE)
by: Coote, S, et al.
Published: (1989)

(±)-Ethyl 6,7-dimethoxy-1-(1H-pyrrol-2-yl)-1,2,3,4-tetrahydroisoquinoline-2-carboxylate
by: Boris Lubomirov Shivachev, et al.
Published: (2008-09-01)

Crystal structure of N-(2,6-diisopropylphenyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide, C22H28N2O
by: Sosibo Sphelele C., et al.
Published: (2014-03-01)

6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline amides and corresponding ester isosteres as multidrug resistance reversers
by: Laura Braconi, et al.
Published: (2020-01-01)

TETRAHYDROISOQUINOLINES .4. ENANTIOSELECTIVE CONVERSION OF (+)-AMPHETAMINE INTO (+)-(1R,3S,4S)-1,2,3,4-TETRAMETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE AND (-)-(1S,3S,4R)-1,2,3,4-TETRAMETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE VIA TRICARBONYL(ARENE)CHROMIUM METHODOLOGY
by: Coote, S, et al.
Published: (1988)

COMPLEMENTARY STEREOSELECTIVE CYCLIZATIONS OF N-(3,4-DIMETHOXYBENZYL)EPHEDRINE AND ITS CHROMIUM TRICARBONYL COMPLEX TO TRANS AND CIS-2,3-DIMETHYL-4-PHENYL-6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINES RESPECTIVELY
by: Coote, S, et al.
Published: (1988)

Ethyl 6-methyl-2-sulfanylidene-4-[4-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carboxylate
by: Susanta K. Nayak, et al.
Published: (2011-07-01)

Crystal structure of 3-hydroxymethyl-1,2,3,4-tetrahydroisoquinolin-1-one
by: Ignez Caracelli, et al.
Published: (2015-08-01)

TETRAHYDROISOQUINOLINES .2. SYNTHESIS OF 4-SUBSTITUTED N-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINES VIA REGIOSELECTIVE AND STEREOSELECTIVE ELABORATION OF TRICARBONYL(N-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE)CHROMIUM
by: Blagg, J, et al.
Published: (1986)

Synthesis and anticonvulsant properties of 1,2,3,4-tetrahydroisoquinolin-1-ones
by: Rosaria Gitto, et al.
Published: (2004-03-01)

2-(2-Iodophenyl)-1,2,3,4-tetrahydroisoquinoline-1-carbonitrile
by: Yanni Ma, et al.
Published: (2011-06-01)

6-Amino-2-methyl-8-phenyl-1,2,3,4-tetrahydroisoquinoline-5,7-dicarbonitrile
by: Dao-Cai Wang, et al.
Published: (2013-06-01)

Synthesis and Contractile Activity of Substituted 1,2,3,4-Tetrahydroisoquinolines
by: Iliyana Stefanova, et al.
Published: (2011-08-01)

4-SUBSTITUTED N-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINES - SYNTHESIS VIA STEREOSELECTIVE SUBSTITUTION OF TRICARBONYL(N-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINE)CHROMIUM
by: Blagg, J, et al.
Published: (1985)

Enantiospecific stereodivergent synthesis of trans- and cis-N(2),3-dimethyl-4-phenyl-1,2,3,4-tetrahydroisoquinolines.
by: Coote, S, et al.
Published: (2010)

N‐phenyl‐1,2,3,4‐tetrahydroisoquinoline:an alternative scaffold for design of 17β‐hydroxysteroid dehydrogenase 1 inhibitors
by: Mottinelli, M, et al.
Published: (2020)

(1-Adamantyl)diphenylmethanol
by: Robert V&#237;cha, et al.
Published: (2010-07-01)

N-(Adamantan-1-yl)-1,2,3,4-tetrahydroisoquinoline-2-carbothioamide
by: Hoong-Kun Fun, et al.
Published: (2013-12-01)

TETRAHYDROISOQUINOLINES .3. STEREOSELECTIVE SYNTHESIS OF CIS- AND TRANS-1,4-DISUBSTITUTED N-METHYL-1,2,3,4-TETRAHYDROISOQUINOLINES AS THEIR TRICARBONYLCHROMIUM COMPLEXES
by: Blagg, J, et al.
Published: (1987)

Crystal structure of [(2S)-1-[(3S)-3-carboxy-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl]-1-oxopropan-2-yl][(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]azanium chloride acetonitrile monosolvate
by: Ai-zhen Li, et al.
Published: (2014-10-01)

Practical and Efficient Synthesis of α-Aminophosphonic Acids Containing 1,2,3,4-Tetrahydroquinoline or 1,2,3,4-Tetrahydroisoquinoline Heterocycles
by: Mario Ordóñez, et al.
Published: (2016-08-01)

N-Benzyl-5-(dimethylamino)naphthalene-1-sulfonamide
by: Pralav Bhatt, et al.
Published: (2011-09-01)

2-Methyl-1,2,3,4-tetrahydroisoquinolin-6-yl N-phenylcarbamate
by: Qiong Xie, et al.
Published: (2009-05-01)

(S)-Methyl 2-[(3R,4R)-2-benzyl-3-(2-furyl)-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxamido]-3-(1H-indol-3-yl)propanoate
by: Zeliha Bakt&#305;r, et al.
Published: (2009-07-01)

[(1R,3S)-3-(1,3-Dithian-2-yl)-2,2-dimethylcyclopropyl]diphenylmethanol
by: Risong Na, et al.
Published: (2009-06-01)

4-Chloro-N-methyl-2-(1,2,3,4-tetrahydroisoquinolin-1-yl)aniline
by: Abdellah Karim, et al.
Published: (2010-12-01)

The effect of chronic 1,2,3,4-Tetrahydroisoquinolines administration in young spontaneously hypertensive rats
by: Abdullah, Aszrin, et al.
Published: (2011)

Microwave-assisted synthesis of 1,2,3,4-tetrahydroisoquinoline sulfonamide derivatives and their biological evaluation
by: Manolov Stanimir P., et al.
Published: (2021-01-01)

(S)-Methyl 2-benzamido-3-(3,4-dimethoxyphenyl)propanoate
by: Tricia Naicker, et al.
Published: (2012-01-01)