Strong renal expression of heat shock protein 70, high mobility group box 1, inducible nitric oxide synthase, and nitrotyrosine in mice model of severe malaria

Strong renal expression of heat shock protein 70, high mobility group box 1, inducible nitric oxide synthase, and nitrotyrosine in mice model of severe malaria

Abstract INTRODUCTION Renal damage is a consequence of severe malaria, and is generally caused by sequestration of Plasmodium falciparum -infected erythrocytes in the renal microcirculation, which leads to obstruction, hypoxia, and ischemia. This triggers high mobility group box 1 (HMGB1) to send a...

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Bibliographic Details
Main Authors: Loeki Enggar Fitri, Ervina Rosmarwati, Yesita Rizky, Niniek Budiarti, Nur Samsu, Karyono Mintaroem
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT)
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
HMGB1
HSP70
iNOS
Nitrotyrosine
Severe malaria
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822017000400489&lng=en&tlng=en

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