Efficacy of pre-emptive peripheral nerve block using 0.25% bupivacaine for postoperative analgesia in patients undergoing maxillofacial surgeries under general anesthesia
Background: Conventional analgesia using non-steroidal anti-inflammatory drugs not only provides inadequate pain relief but also can produce a multitude of systemic adverse effects. During oral and maxillofacial surgeries, inhibition of central sensitization by pre-incision nerve blocks with local a...
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| Format: | Article |
| Language: | English |
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Manipal College of Medical Sciences, Pokhara
2023-09-01
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| Series: | Asian Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/46132 |
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| author | Lini Srivastava Soumyadip Pal Saikat Majumdar Soma Chakraborty Kaushal Kabir Manabendra Sarkar Jati Sankar Rudra |
| author_facet | Lini Srivastava Soumyadip Pal Saikat Majumdar Soma Chakraborty Kaushal Kabir Manabendra Sarkar Jati Sankar Rudra |
| author_sort | Lini Srivastava |
| collection | DOAJ |
| description | Background: Conventional analgesia using non-steroidal anti-inflammatory drugs not only provides inadequate pain relief but also can produce a multitude of systemic adverse effects. During oral and maxillofacial surgeries, inhibition of central sensitization by pre-incision nerve blocks with local anesthetic can reduce postoperative pain, may curtail analgesic requirement, and thereby can provide better patient comfort.
Aims and Objectives: This study aimed to evaluate the effectiveness of pre-incisional peripheral nerve block using 0.25% bupivacaine over placebo for postoperative pain relief in patients undergoing oral and maxillofacial surgery under general anesthesia.
Materials and Methods: One hundred and twenty patients of 18–35 years of either sex, American Society of Anesthesiologists physical status class I and II had undergone oral and maxillofacial surgeries were divided into two groups to receive bupivacaine 0.25% (Study group, n=60) normal saline (Control group, n=60) for nerve block before surgical incision. Postoperative pain was assessed by Visual Analog Scale (VAS) score and verbal response scale (VRS) score. The number of rescue analgesia was required in the first 24 h and the incidence of any complications associated with this agent was documented.
Results: The VAS score was found considerably lower in the bupivacaine group compared with the control group in the first 24 h of postoperative period (P<0.05). A similar trend was observed with VRS score in the first 16 h of postoperative period (P<0.05). The number of rescue analgesia required in the control group was much higher in comparison with the study group. There was no serious adverse event in both the groups.
Conclusion: Bupivacaine 0.25% as pre-emptive analgesia can be used to reduce postoperative pain and analgesic requirements in maxillofacial surgeries. |
| first_indexed | 2024-03-12T11:21:00Z |
| format | Article |
| id | doaj.art-97df5787c89d4cb0b1b66ce262c25480 |
| institution | Directory Open Access Journal |
| issn | 2467-9100 2091-0576 |
| language | English |
| last_indexed | 2024-03-12T11:21:00Z |
| publishDate | 2023-09-01 |
| publisher | Manipal College of Medical Sciences, Pokhara |
| record_format | Article |
| series | Asian Journal of Medical Sciences |
| spelling | doaj.art-97df5787c89d4cb0b1b66ce262c254802023-09-01T23:41:49ZengManipal College of Medical Sciences, PokharaAsian Journal of Medical Sciences2467-91002091-05762023-09-011492630https://doi.org/10.3126/ajms.v14i9.46132Efficacy of pre-emptive peripheral nerve block using 0.25% bupivacaine for postoperative analgesia in patients undergoing maxillofacial surgeries under general anesthesiaLini Srivastava 0https://orcid.org/0009-0008-9032-8072Soumyadip Pal 1https://orcid.org/0009-0001-3236-3039Saikat Majumdar 2https://orcid.org/0000-0002-4368-9990Soma Chakraborty 3https://orcid.org/0000-0003-0253-5183Kaushal Kabir 4https://orcid.org/0000-0002-5141-0187Manabendra Sarkar 5https://orcid.org/0009-0002-9060-1661Jati Sankar Rudra 6https://orcid.org/0009-0006-1892-8773Senior Resident, Department of Anesthesiology, Nilratan Sircar Medical College, Kolkata, West Bengal, India Senior Resident, Department of Anesthesiology, Nilratan Sircar Medical College, Kolkata, West Bengal, India Associate Professor, Department of Anesthesiology, Nilratan Sircar Medical College, Kolkata, West Bengal, India Associate Professor, Department of Anesthesiology, IPGME and R/SSKM Hospital, Kolkata, West Bengal, India Associate Professor, Department of Anesthesiology, M.G.M. Medical College and Hospital, Indore, Madhya Pradesh, India Professor, Department of Anesthesiology, Nilratan Sircar Medical College, Kolkata, West Bengal, India Professor, Department of Anesthesiology, Nilratan Sircar Medical College, Kolkata, West Bengal, India Background: Conventional analgesia using non-steroidal anti-inflammatory drugs not only provides inadequate pain relief but also can produce a multitude of systemic adverse effects. During oral and maxillofacial surgeries, inhibition of central sensitization by pre-incision nerve blocks with local anesthetic can reduce postoperative pain, may curtail analgesic requirement, and thereby can provide better patient comfort. Aims and Objectives: This study aimed to evaluate the effectiveness of pre-incisional peripheral nerve block using 0.25% bupivacaine over placebo for postoperative pain relief in patients undergoing oral and maxillofacial surgery under general anesthesia. Materials and Methods: One hundred and twenty patients of 18–35 years of either sex, American Society of Anesthesiologists physical status class I and II had undergone oral and maxillofacial surgeries were divided into two groups to receive bupivacaine 0.25% (Study group, n=60) normal saline (Control group, n=60) for nerve block before surgical incision. Postoperative pain was assessed by Visual Analog Scale (VAS) score and verbal response scale (VRS) score. The number of rescue analgesia was required in the first 24 h and the incidence of any complications associated with this agent was documented. Results: The VAS score was found considerably lower in the bupivacaine group compared with the control group in the first 24 h of postoperative period (P<0.05). A similar trend was observed with VRS score in the first 16 h of postoperative period (P<0.05). The number of rescue analgesia required in the control group was much higher in comparison with the study group. There was no serious adverse event in both the groups. Conclusion: Bupivacaine 0.25% as pre-emptive analgesia can be used to reduce postoperative pain and analgesic requirements in maxillofacial surgeries.https://www.nepjol.info/index.php/AJMS/article/view/46132pre-emptive; visual analogue scale; verbal response scale; maxillo-facial surgery |
| spellingShingle | Lini Srivastava Soumyadip Pal Saikat Majumdar Soma Chakraborty Kaushal Kabir Manabendra Sarkar Jati Sankar Rudra Efficacy of pre-emptive peripheral nerve block using 0.25% bupivacaine for postoperative analgesia in patients undergoing maxillofacial surgeries under general anesthesia Asian Journal of Medical Sciences pre-emptive; visual analogue scale; verbal response scale; maxillo-facial surgery |
| title | Efficacy of pre-emptive peripheral nerve block using 0.25% bupivacaine for postoperative analgesia in patients undergoing maxillofacial surgeries under general anesthesia |
| title_full | Efficacy of pre-emptive peripheral nerve block using 0.25% bupivacaine for postoperative analgesia in patients undergoing maxillofacial surgeries under general anesthesia |
| title_fullStr | Efficacy of pre-emptive peripheral nerve block using 0.25% bupivacaine for postoperative analgesia in patients undergoing maxillofacial surgeries under general anesthesia |
| title_full_unstemmed | Efficacy of pre-emptive peripheral nerve block using 0.25% bupivacaine for postoperative analgesia in patients undergoing maxillofacial surgeries under general anesthesia |
| title_short | Efficacy of pre-emptive peripheral nerve block using 0.25% bupivacaine for postoperative analgesia in patients undergoing maxillofacial surgeries under general anesthesia |
| title_sort | efficacy of pre emptive peripheral nerve block using 0 25 bupivacaine for postoperative analgesia in patients undergoing maxillofacial surgeries under general anesthesia |
| topic | pre-emptive; visual analogue scale; verbal response scale; maxillo-facial surgery |
| url | https://www.nepjol.info/index.php/AJMS/article/view/46132 |
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