Sulfur-Containing Compounds from Endophytic Fungi: Sources, Structures and Bioactivities
Endophytic fungi have attracted increasing attention as an under-explored source for the discovery and development of structurally and functionally diverse secondary metabolites. These microorganisms colonize their hosts, primarily plants, and demonstrate diverse ecological distribution. Among endop...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Journal of Fungi |
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| Online Access: | https://www.mdpi.com/2309-608X/8/6/628 |
| _version_ | 1797485637117411328 |
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| author | Yaqin Fan Zhiheng Ma Yan Zhang Yufei Wang Yousong Ding Cong Wang Shugeng Cao |
| author_facet | Yaqin Fan Zhiheng Ma Yan Zhang Yufei Wang Yousong Ding Cong Wang Shugeng Cao |
| author_sort | Yaqin Fan |
| collection | DOAJ |
| description | Endophytic fungi have attracted increasing attention as an under-explored source for the discovery and development of structurally and functionally diverse secondary metabolites. These microorganisms colonize their hosts, primarily plants, and demonstrate diverse ecological distribution. Among endophytic fungal natural products, sulfur-containing compounds feature one or more sulfur atoms and possess a range of bioactivities, e.g., cytotoxicity and antimicrobial activities. These natural products mainly belong to the classes of polyketides, nonribosomal peptides, terpenoids, and hybrids. Here, we reviewed the fungal producers, plant sources, chemical structures, and bioactivities of 143 new sulfur-containing compounds that were reported from 1985 to March 2022. |
| first_indexed | 2024-03-09T23:22:00Z |
| format | Article |
| id | doaj.art-97e1566333ee4c3e8c9a4da8a5af74b6 |
| institution | Directory Open Access Journal |
| issn | 2309-608X |
| language | English |
| last_indexed | 2024-03-09T23:22:00Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Fungi |
| spelling | doaj.art-97e1566333ee4c3e8c9a4da8a5af74b62023-11-23T17:25:16ZengMDPI AGJournal of Fungi2309-608X2022-06-018662810.3390/jof8060628Sulfur-Containing Compounds from Endophytic Fungi: Sources, Structures and BioactivitiesYaqin Fan0Zhiheng Ma1Yan Zhang2Yufei Wang3Yousong Ding4Cong Wang5Shugeng Cao6Shandong Provincial Key Laboratory of Applied Mycology, School of Life Sciences, Qingdao Agricultural University, Qingdao 266109, ChinaShandong Provincial Key Laboratory of Applied Mycology, School of Life Sciences, Qingdao Agricultural University, Qingdao 266109, ChinaShandong Provincial Key Laboratory of Applied Mycology, School of Life Sciences, Qingdao Agricultural University, Qingdao 266109, ChinaKey Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, School of Chemistry and Chemical Engineering, Guangxi Minzu University, Nanning 530006, ChinaDepartment of Medicinal Chemistry, Center for Natural Products, Drug Discovery and Development, College of Pharmacy, University of Florida, Gainesville, FL 32610, USAKey Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, School of Chemistry and Chemical Engineering, Guangxi Minzu University, Nanning 530006, ChinaDepartment of Pharmaceutical Sciences, Daniel K. Inouye College of Pharmacy, University of Hawai’i at Hilo, 200 W. Kawili St., Hilo, HI 96720, USAEndophytic fungi have attracted increasing attention as an under-explored source for the discovery and development of structurally and functionally diverse secondary metabolites. These microorganisms colonize their hosts, primarily plants, and demonstrate diverse ecological distribution. Among endophytic fungal natural products, sulfur-containing compounds feature one or more sulfur atoms and possess a range of bioactivities, e.g., cytotoxicity and antimicrobial activities. These natural products mainly belong to the classes of polyketides, nonribosomal peptides, terpenoids, and hybrids. Here, we reviewed the fungal producers, plant sources, chemical structures, and bioactivities of 143 new sulfur-containing compounds that were reported from 1985 to March 2022.https://www.mdpi.com/2309-608X/8/6/628sulfurplant endophyteendophytic fungi |
| spellingShingle | Yaqin Fan Zhiheng Ma Yan Zhang Yufei Wang Yousong Ding Cong Wang Shugeng Cao Sulfur-Containing Compounds from Endophytic Fungi: Sources, Structures and Bioactivities Journal of Fungi sulfur plant endophyte endophytic fungi |
| title | Sulfur-Containing Compounds from Endophytic Fungi: Sources, Structures and Bioactivities |
| title_full | Sulfur-Containing Compounds from Endophytic Fungi: Sources, Structures and Bioactivities |
| title_fullStr | Sulfur-Containing Compounds from Endophytic Fungi: Sources, Structures and Bioactivities |
| title_full_unstemmed | Sulfur-Containing Compounds from Endophytic Fungi: Sources, Structures and Bioactivities |
| title_short | Sulfur-Containing Compounds from Endophytic Fungi: Sources, Structures and Bioactivities |
| title_sort | sulfur containing compounds from endophytic fungi sources structures and bioactivities |
| topic | sulfur plant endophyte endophytic fungi |
| url | https://www.mdpi.com/2309-608X/8/6/628 |
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