Antioxidant and C5a-blocking strategy for hepatic ischemia–reperfusion injury repair

Antioxidant and C5a-blocking strategy for hepatic ischemia–reperfusion injury repair

Abstract Background Nonspecific liver uptake of nanomaterials after intravenous injection has hindered nanomedicine for clinical translation. However, nanomaterials’ propensity for liver distribution might enable their use in hepatic ischemia–reperfusion injury (IRI) repair. During hepatic IRI, reac...

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Bibliographic Details
Main Authors: Xiaobing Zhang, Jiajia Hu, Kaelyn V. Becker, Jonathan W. Engle, Dalong Ni, Weibo Cai, Dong Wu, Shuping Qu
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Nanobiotechnology
Subjects:
Hepatic ischemia–reperfusion injury
Nanoantioxidants
C5a
Nanoceria
Aptamer
Online Access:https://doi.org/10.1186/s12951-021-00858-9

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