Circulating levels of vitamin D3 and leptin in lean infertile women with polycystic ovary syndrome
Objective: The objective of this study is to measure levels of Vitamin D3 and leptin and assess their relation of each to the pathogenesis of polycystic ovary syndrome (PCOS). Design: This was a cohort observational study. Settings: This study was conducted at the Department of Obstetrics and Gyneco...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Journal of Human Reproductive Sciences |
| Subjects: | |
| Online Access: | http://www.jhrsonline.org/article.asp?issn=0974-1208;year=2018;volume=11;issue=4;spage=343;epage=347;aulast=Dawood |
| _version_ | 1811256535721967616 |
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| author | Ayman Shehata Dawood Adel Elgergawy Ahmed Elhalwagy |
| author_facet | Ayman Shehata Dawood Adel Elgergawy Ahmed Elhalwagy |
| author_sort | Ayman Shehata Dawood |
| collection | DOAJ |
| description | Objective: The objective of this study is to measure levels of Vitamin D3 and leptin and assess their relation of each to the pathogenesis of polycystic ovary syndrome (PCOS). Design: This was a cohort observational study. Settings: This study was conducted at the Department of Obstetrics and Gynecology, Tanta University. Materials and Methods: Ninety lean women were enrolled in this study and were allocated into two groups with 45 patients in each group: the first group (study group) who are lean women with PCOS and the second group (control group) who are the lean infertile patients without PCOS. Blood samples were collected and tested for study parameters. Results: There were no significant differences regarding demographic characteristics between both groups. The differences were in ovarian volume and hormonal profiles. Serum leptin was found to be significantly increased in lean PCOS than in control groups. Vitamin D3 levels were found to be lower in the lean PCOS group than in control group. Conclusion: Lean PCOS women are a unique group with specific hormonal profiles different from the typical PCOS profiles. Leptin and Vitamin D3 may have a role in the pathogenesis of lean PCOS, but large studies are still required regarding this unique group. |
| first_indexed | 2024-04-12T17:42:29Z |
| format | Article |
| id | doaj.art-97e3d12fae9f4b0099b4ae595e8ff163 |
| institution | Directory Open Access Journal |
| issn | 0974-1208 1998-4766 |
| language | English |
| last_indexed | 2024-04-12T17:42:29Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Human Reproductive Sciences |
| spelling | doaj.art-97e3d12fae9f4b0099b4ae595e8ff1632022-12-22T03:22:46ZengWolters Kluwer Medknow PublicationsJournal of Human Reproductive Sciences0974-12081998-47662018-01-0111434334710.4103/jhrs.JHRS_40_18Circulating levels of vitamin D3 and leptin in lean infertile women with polycystic ovary syndromeAyman Shehata DawoodAdel ElgergawyAhmed ElhalwagyObjective: The objective of this study is to measure levels of Vitamin D3 and leptin and assess their relation of each to the pathogenesis of polycystic ovary syndrome (PCOS). Design: This was a cohort observational study. Settings: This study was conducted at the Department of Obstetrics and Gynecology, Tanta University. Materials and Methods: Ninety lean women were enrolled in this study and were allocated into two groups with 45 patients in each group: the first group (study group) who are lean women with PCOS and the second group (control group) who are the lean infertile patients without PCOS. Blood samples were collected and tested for study parameters. Results: There were no significant differences regarding demographic characteristics between both groups. The differences were in ovarian volume and hormonal profiles. Serum leptin was found to be significantly increased in lean PCOS than in control groups. Vitamin D3 levels were found to be lower in the lean PCOS group than in control group. Conclusion: Lean PCOS women are a unique group with specific hormonal profiles different from the typical PCOS profiles. Leptin and Vitamin D3 may have a role in the pathogenesis of lean PCOS, but large studies are still required regarding this unique group.http://www.jhrsonline.org/article.asp?issn=0974-1208;year=2018;volume=11;issue=4;spage=343;epage=347;aulast=DawoodLeanleptinpathogenesispolycystic ovary syndromeVitamin D3 |
| spellingShingle | Ayman Shehata Dawood Adel Elgergawy Ahmed Elhalwagy Circulating levels of vitamin D3 and leptin in lean infertile women with polycystic ovary syndrome Journal of Human Reproductive Sciences Lean leptin pathogenesis polycystic ovary syndrome Vitamin D3 |
| title | Circulating levels of vitamin D3 and leptin in lean infertile women with polycystic ovary syndrome |
| title_full | Circulating levels of vitamin D3 and leptin in lean infertile women with polycystic ovary syndrome |
| title_fullStr | Circulating levels of vitamin D3 and leptin in lean infertile women with polycystic ovary syndrome |
| title_full_unstemmed | Circulating levels of vitamin D3 and leptin in lean infertile women with polycystic ovary syndrome |
| title_short | Circulating levels of vitamin D3 and leptin in lean infertile women with polycystic ovary syndrome |
| title_sort | circulating levels of vitamin d3 and leptin in lean infertile women with polycystic ovary syndrome |
| topic | Lean leptin pathogenesis polycystic ovary syndrome Vitamin D3 |
| url | http://www.jhrsonline.org/article.asp?issn=0974-1208;year=2018;volume=11;issue=4;spage=343;epage=347;aulast=Dawood |
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