TMP269, a small molecule inhibitor of class IIa HDAC, suppresses RABV replication in vitro

TMP269, a small molecule inhibitor of class IIa HDAC, suppresses RABV replication in vitro

TMP269, a small molecular inhibitor of IIa histone deacetylase, plays a vital role in cancer therapeutic. However, the effect of TMP269 on the regulation of viral replication has not been studied. In the present study, we found that TMP269 treatment significantly inhibited RABV replication at concen...

Full description

Bibliographic Details
Main Authors: Juanbin Yin, Shasha Wang, Shanhui Ren, Zhengji Liang, Junwei Ge, Yuefeng Sun, Xiangping Yin, Xiangwei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Microbiology
Subjects:
histone deacetylase inhibitor
TMP269
rabies virus (RABV)
antiviral
autophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1284439/full

Similar Items

Similar Items