Resected primary mucinous cholangiocarcinoma of the liver
Abstract Background Mucinous cholangiocarcinoma (MC) is a very rare variant of intrahepatic cholangiocarcinoma. MC is characterized by rapid growth, widespread metastasis, and poor prognosis. We report a case of resected MC of the liver. Case presentation We found a 13.6-cm hypovascular tumor in the...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2018-05-01
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| Series: | Surgical Case Reports |
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| Online Access: | http://link.springer.com/article/10.1186/s40792-018-0450-3 |
| _version_ | 1818678119733657600 |
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| author | Kei Hagiwara Kenichiro Araki Takahiro Yamanaka Norihiro Ishii Takamichi Igarashi Akira Watanabe Norio Kubo Norifumi Harimoto Hiroyuki Kuwano Sumito Nobusawa Shinichi Aishima Ken Shirabe |
| author_facet | Kei Hagiwara Kenichiro Araki Takahiro Yamanaka Norihiro Ishii Takamichi Igarashi Akira Watanabe Norio Kubo Norifumi Harimoto Hiroyuki Kuwano Sumito Nobusawa Shinichi Aishima Ken Shirabe |
| author_sort | Kei Hagiwara |
| collection | DOAJ |
| description | Abstract Background Mucinous cholangiocarcinoma (MC) is a very rare variant of intrahepatic cholangiocarcinoma. MC is characterized by rapid growth, widespread metastasis, and poor prognosis. We report a case of resected MC of the liver. Case presentation We found a 13.6-cm hypovascular tumor in the left hepatic lobe of a 68-year-old man, which we initially diagnosed as a mass-forming intrahepatic cholangiocarcinoma. Left lobe and caudate resection was performed without major intraoperative or postoperative complications. He was discharged home on postoperative day 9 and had no recurrence for 6 months. Pathological examination showed a mucous lobulated tumor with abundant mucus in the cytoplasm and extracellular regions. After differential diagnosis that considered invasive intraductal papillary neoplasm of the bile duct and metastatic liver tumors from the digestive tract, this tumor was diagnosed as a cholangiocarcinoma rare variant: primary mucinous carcinoma of the liver. Conclusion Analysis of previous reports suggests that primary MC of the liver could be classified into two subtypes: pure MC and combined hepatocellular carcinoma and MC. Notably, the latter has been reported only in patients with chronic liver disease, whereas the former has only been reported in patients with no underlying disease. |
| first_indexed | 2024-12-17T09:10:12Z |
| format | Article |
| id | doaj.art-97e9ae4080384cb8b0de58667be60271 |
| institution | Directory Open Access Journal |
| issn | 2198-7793 |
| language | English |
| last_indexed | 2024-12-17T09:10:12Z |
| publishDate | 2018-05-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj.art-97e9ae4080384cb8b0de58667be602712022-12-21T21:55:16ZengSpringerOpenSurgical Case Reports2198-77932018-05-01411510.1186/s40792-018-0450-3Resected primary mucinous cholangiocarcinoma of the liverKei Hagiwara0Kenichiro Araki1Takahiro Yamanaka2Norihiro Ishii3Takamichi Igarashi4Akira Watanabe5Norio Kubo6Norifumi Harimoto7Hiroyuki Kuwano8Sumito Nobusawa9Shinichi Aishima10Ken Shirabe11Hepatobiliary and Pancreatic Surgery, Gunma University Graduate School of MedicineHepatobiliary and Pancreatic Surgery, Gunma University Graduate School of MedicineHepatobiliary and Pancreatic Surgery, Gunma University Graduate School of MedicineHepatobiliary and Pancreatic Surgery, Gunma University Graduate School of MedicineHepatobiliary and Pancreatic Surgery, Gunma University Graduate School of MedicineHepatobiliary and Pancreatic Surgery, Gunma University Graduate School of MedicineHepatobiliary and Pancreatic Surgery, Gunma University Graduate School of MedicineHepatobiliary and Pancreatic Surgery, Gunma University Graduate School of MedicineGeneral Surgical Science, Gunma University Graduate School of MedicineDepartment of Human Pathology, Gunma University Graduate School of MedicinePathology and Microbiology, Saga UniversityHepatobiliary and Pancreatic Surgery, Gunma University Graduate School of MedicineAbstract Background Mucinous cholangiocarcinoma (MC) is a very rare variant of intrahepatic cholangiocarcinoma. MC is characterized by rapid growth, widespread metastasis, and poor prognosis. We report a case of resected MC of the liver. Case presentation We found a 13.6-cm hypovascular tumor in the left hepatic lobe of a 68-year-old man, which we initially diagnosed as a mass-forming intrahepatic cholangiocarcinoma. Left lobe and caudate resection was performed without major intraoperative or postoperative complications. He was discharged home on postoperative day 9 and had no recurrence for 6 months. Pathological examination showed a mucous lobulated tumor with abundant mucus in the cytoplasm and extracellular regions. After differential diagnosis that considered invasive intraductal papillary neoplasm of the bile duct and metastatic liver tumors from the digestive tract, this tumor was diagnosed as a cholangiocarcinoma rare variant: primary mucinous carcinoma of the liver. Conclusion Analysis of previous reports suggests that primary MC of the liver could be classified into two subtypes: pure MC and combined hepatocellular carcinoma and MC. Notably, the latter has been reported only in patients with chronic liver disease, whereas the former has only been reported in patients with no underlying disease.http://link.springer.com/article/10.1186/s40792-018-0450-3Combined carcinomaIntraductal papillary neoplasm of the bile ductMetastatic liver tumorsMucinous cholangiocarcinoma |
| spellingShingle | Kei Hagiwara Kenichiro Araki Takahiro Yamanaka Norihiro Ishii Takamichi Igarashi Akira Watanabe Norio Kubo Norifumi Harimoto Hiroyuki Kuwano Sumito Nobusawa Shinichi Aishima Ken Shirabe Resected primary mucinous cholangiocarcinoma of the liver Surgical Case Reports Combined carcinoma Intraductal papillary neoplasm of the bile duct Metastatic liver tumors Mucinous cholangiocarcinoma |
| title | Resected primary mucinous cholangiocarcinoma of the liver |
| title_full | Resected primary mucinous cholangiocarcinoma of the liver |
| title_fullStr | Resected primary mucinous cholangiocarcinoma of the liver |
| title_full_unstemmed | Resected primary mucinous cholangiocarcinoma of the liver |
| title_short | Resected primary mucinous cholangiocarcinoma of the liver |
| title_sort | resected primary mucinous cholangiocarcinoma of the liver |
| topic | Combined carcinoma Intraductal papillary neoplasm of the bile duct Metastatic liver tumors Mucinous cholangiocarcinoma |
| url | http://link.springer.com/article/10.1186/s40792-018-0450-3 |
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