Is beta-carotene consumption associated with thyroid hormone levels?
The thyroid hormones play a pivotal role in various physiological processes, including growth, metabolism regulation, and reproduction. While non-modifiable factors are known to impact thyroid function, such as genetics and age, nutritional factors are also important. Diets rich in selenium and iodi...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2023.1089315/full |
| _version_ | 1797819829962407936 |
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| author | Bahareh Farasati Far Nima Broomand Lomer Hossein Gharedaghi Hadi Sahrai Golnaz Mahmoudvand Golnaz Mahmoudvand Arian Karimi Rouzbahani Arian Karimi Rouzbahani |
| author_facet | Bahareh Farasati Far Nima Broomand Lomer Hossein Gharedaghi Hadi Sahrai Golnaz Mahmoudvand Golnaz Mahmoudvand Arian Karimi Rouzbahani Arian Karimi Rouzbahani |
| author_sort | Bahareh Farasati Far |
| collection | DOAJ |
| description | The thyroid hormones play a pivotal role in various physiological processes, including growth, metabolism regulation, and reproduction. While non-modifiable factors are known to impact thyroid function, such as genetics and age, nutritional factors are also important. Diets rich in selenium and iodine are conventionally acknowledged to be beneficial for the production and release of thyroid hormones. Recent studies have suggested a potential link between beta-carotene, a precursor to vitamin A (retinol), and thyroid function. Beta-carotene is known for its antioxidant properties and has been shown to play a role in the prevention of various clinical conditions such as cancer and cardiovascular and neurological diseases. However, its impact on thyroid function is still unclear. Some studies have suggested a positive association between beta-carotene levels and thyroid function, while others have found no significant effect. Conversely, the hormone produced by the thyroid gland, thyroxine, enhances the conversion of beta-carotene to retinol. Furthermore, vitamin A derivatives are being explored as potential therapeutic options for thyroid malignancies. In this review, we highlight the mechanisms through which beta-carotene/retinol and thyroid hormones interact and review the findings of clinical studies examining the association between beta-carotene consumption and thyroid hormone levels. Our review underscores the need for further research to clarify the relationship between beta-carotene and thyroid function. |
| first_indexed | 2024-03-13T09:28:24Z |
| format | Article |
| id | doaj.art-97eb1a41117e4237bfd6c1cd6087f192 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-03-13T09:28:24Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-97eb1a41117e4237bfd6c1cd6087f1922023-05-26T04:43:16ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922023-05-011410.3389/fendo.2023.10893151089315Is beta-carotene consumption associated with thyroid hormone levels?Bahareh Farasati Far0Nima Broomand Lomer1Hossein Gharedaghi2Hadi Sahrai3Golnaz Mahmoudvand4Golnaz Mahmoudvand5Arian Karimi Rouzbahani6Arian Karimi Rouzbahani7Department of Chemistry, Iran University of Science and Technology, Tehran, IranFaculty of Medicine, Guilan University of Medical Sciences, Guilan, IranSchool of Medicine, Zanjan University of Medical Sciences, Zanjan, IranStudent Research Committee, Tabriz University of Medical Sciences, Tabriz, IranStudent Research Committee, Lorestan University of Medical Sciences, Khorramabad, IranUSERN Office, Lorestan University of Medical Sciences, Khorramabad, IranStudent Research Committee, Lorestan University of Medical Sciences, Khorramabad, IranUSERN Office, Lorestan University of Medical Sciences, Khorramabad, IranThe thyroid hormones play a pivotal role in various physiological processes, including growth, metabolism regulation, and reproduction. While non-modifiable factors are known to impact thyroid function, such as genetics and age, nutritional factors are also important. Diets rich in selenium and iodine are conventionally acknowledged to be beneficial for the production and release of thyroid hormones. Recent studies have suggested a potential link between beta-carotene, a precursor to vitamin A (retinol), and thyroid function. Beta-carotene is known for its antioxidant properties and has been shown to play a role in the prevention of various clinical conditions such as cancer and cardiovascular and neurological diseases. However, its impact on thyroid function is still unclear. Some studies have suggested a positive association between beta-carotene levels and thyroid function, while others have found no significant effect. Conversely, the hormone produced by the thyroid gland, thyroxine, enhances the conversion of beta-carotene to retinol. Furthermore, vitamin A derivatives are being explored as potential therapeutic options for thyroid malignancies. In this review, we highlight the mechanisms through which beta-carotene/retinol and thyroid hormones interact and review the findings of clinical studies examining the association between beta-carotene consumption and thyroid hormone levels. Our review underscores the need for further research to clarify the relationship between beta-carotene and thyroid function.https://www.frontiersin.org/articles/10.3389/fendo.2023.1089315/fullbeta carotenethyroid hormone levelsthyroid cancerhormonal imbalancevitamin Aretinol |
| spellingShingle | Bahareh Farasati Far Nima Broomand Lomer Hossein Gharedaghi Hadi Sahrai Golnaz Mahmoudvand Golnaz Mahmoudvand Arian Karimi Rouzbahani Arian Karimi Rouzbahani Is beta-carotene consumption associated with thyroid hormone levels? Frontiers in Endocrinology beta carotene thyroid hormone levels thyroid cancer hormonal imbalance vitamin A retinol |
| title | Is beta-carotene consumption associated with thyroid hormone levels? |
| title_full | Is beta-carotene consumption associated with thyroid hormone levels? |
| title_fullStr | Is beta-carotene consumption associated with thyroid hormone levels? |
| title_full_unstemmed | Is beta-carotene consumption associated with thyroid hormone levels? |
| title_short | Is beta-carotene consumption associated with thyroid hormone levels? |
| title_sort | is beta carotene consumption associated with thyroid hormone levels |
| topic | beta carotene thyroid hormone levels thyroid cancer hormonal imbalance vitamin A retinol |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2023.1089315/full |
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