Exercise Reduces the Resumption of Tumor Growth and Proteolytic Pathways in the Skeletal Muscle of Mice Following Chemotherapy

Exercise Reduces the Resumption of Tumor Growth and Proteolytic Pathways in the Skeletal Muscle of Mice Following Chemotherapy

The pathogenesis of muscle atrophy plays a central role in cancer cachexia, and chemotherapy contributes to this condition. Therefore, the present study aimed to evaluate the effects of endurance exercise on time-dependent muscle atrophy caused by doxorubicin. For this, C57 BL/6 mice were subcutaneo...

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Bibliographic Details
Main Authors: Edson Alves de Lima, Alexandre Abilio de Souza Teixeira, Luana Amorim Biondo, Tiego Aparecido Diniz, Loreana Sanches Silveira, Dario Coletti, Silvia Busquets Rius, José Cesar Rosa Neto
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
doxorubicin
chemotherapy
endurance exercise
Lewis lung carcinoma
tumor
skeletal muscle
Online Access:https://www.mdpi.com/2072-6694/12/11/3466

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