Revealing hidden information in osteoblast’s mechanotransduction through analysis of time patterns of critical events

Revealing hidden information in osteoblast’s mechanotransduction through analysis of time patterns of critical events

Abstract Background Mechanotransduction in bone cells plays a pivotal role in osteoblast differentiation and bone remodelling. Mechanotransduction provides the link between modulation of the extracellular matrix by mechanical load and intracellular activity. By controlling the balance between the in...

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Bibliographic Details
Main Authors: Gianluca Ascolani, Timothy M. Skerry, Damien Lacroix, Enrico Dall’Ara, Aban Shuaib
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Bioinformatics
Subjects:
Osteoblast mechanotransduction
Molecular network
Fluctuations
Subordination theory
Directing process
Waiting time distribution
Online Access:http://link.springer.com/article/10.1186/s12859-020-3394-0

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