Imaging and detecting intercellular tensile forces in spheroids and embryoid bodies using lipid-modified DNA probes

Imaging and detecting intercellular tensile forces in spheroids and embryoid bodies using lipid-modified DNA probes

Cells continuously experience and respond to different physical forces that are used to regulate their physiology and functions. Our ability to measure these mechanical cues is essential for understanding the bases of various mechanosensing and mechanotransduction processes. While multiple strategie...

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Bibliographic Details
Main Authors: Qian Tian, Feiyu Yang, Han Jiang, Priyanka Bhattacharyya, Tianfa Xie, Ahsan Ausaf Ali, Yubing Sun, Mingxu You
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
cell-cell junction
DNA probes
fluorescence imaging
mechanotransduction
tensile forces
3D cell model
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1220079/full

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