Systemic lupus erythematosus in Latin America: Outcomes and therapeutic challenges
Systemic lupus erythematosus (SLE) affects more severely non-White populations, which is also the case in Latin America; this is the result of a combination of genetic and non-genetic factors. Among the non-genetic factors, a limited income and a low educational level impact negatively on the course...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Clinical Immunology Communications |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772613423000264 |
| _version_ | 1797653500929245184 |
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| author | Manuel F. Ugarte-Gil Graciela S. Alarcón |
| author_facet | Manuel F. Ugarte-Gil Graciela S. Alarcón |
| author_sort | Manuel F. Ugarte-Gil |
| collection | DOAJ |
| description | Systemic lupus erythematosus (SLE) affects more severely non-White populations, which is also the case in Latin America; this is the result of a combination of genetic and non-genetic factors. Among the non-genetic factors, a limited income and a low educational level impact negatively on the course and outcome of the disease; in addition, lack of access to healthcare services deprives patients from the opportunity of being managed by specialists, making the availability of the newest drugs practically impossible. Taking together, these factors reduce the probability of patients achieving good outcomes, like remission, less damage accrual, a better survival and a better health-related quality of life, among others. Several strategies have been proposed to reduce these disparities, including peer education, educational activities for patients and primary care physicians, improving healthcare networks and generating cost-effectiveness analyses. |
| first_indexed | 2024-03-11T16:45:28Z |
| format | Article |
| id | doaj.art-97fc529944ce4bd699bb7a58f60271dc |
| institution | Directory Open Access Journal |
| issn | 2772-6134 |
| language | English |
| last_indexed | 2024-03-11T16:45:28Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical Immunology Communications |
| spelling | doaj.art-97fc529944ce4bd699bb7a58f60271dc2023-10-23T04:08:06ZengElsevierClinical Immunology Communications2772-61342023-12-0146064Systemic lupus erythematosus in Latin America: Outcomes and therapeutic challengesManuel F. Ugarte-Gil0Graciela S. Alarcón1Rheumatology Department, Hospital Guillermo Almenara Irigoyen. EsSalud. Lima, Peru; Grupo Peruano de Estudio de Enfermedades Autoinmunes Sistémicas, Universidad Científica del Sur. Lima, Peru; Corresponding author at: Universidad Científica del Sur, Av. Panamericana Sur Km 19. Villa El Salvador 15067, Lima-Perú.Marnix E. Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL United States; School of Medicine, Universidad Peruana Cayetano Heredia, Lima, PeruSystemic lupus erythematosus (SLE) affects more severely non-White populations, which is also the case in Latin America; this is the result of a combination of genetic and non-genetic factors. Among the non-genetic factors, a limited income and a low educational level impact negatively on the course and outcome of the disease; in addition, lack of access to healthcare services deprives patients from the opportunity of being managed by specialists, making the availability of the newest drugs practically impossible. Taking together, these factors reduce the probability of patients achieving good outcomes, like remission, less damage accrual, a better survival and a better health-related quality of life, among others. Several strategies have been proposed to reduce these disparities, including peer education, educational activities for patients and primary care physicians, improving healthcare networks and generating cost-effectiveness analyses.http://www.sciencedirect.com/science/article/pii/S2772613423000264Systemic lupus erythematosusOutcomesHispanicLatin AmericaTreatment |
| spellingShingle | Manuel F. Ugarte-Gil Graciela S. Alarcón Systemic lupus erythematosus in Latin America: Outcomes and therapeutic challenges Clinical Immunology Communications Systemic lupus erythematosus Outcomes Hispanic Latin America Treatment |
| title | Systemic lupus erythematosus in Latin America: Outcomes and therapeutic challenges |
| title_full | Systemic lupus erythematosus in Latin America: Outcomes and therapeutic challenges |
| title_fullStr | Systemic lupus erythematosus in Latin America: Outcomes and therapeutic challenges |
| title_full_unstemmed | Systemic lupus erythematosus in Latin America: Outcomes and therapeutic challenges |
| title_short | Systemic lupus erythematosus in Latin America: Outcomes and therapeutic challenges |
| title_sort | systemic lupus erythematosus in latin america outcomes and therapeutic challenges |
| topic | Systemic lupus erythematosus Outcomes Hispanic Latin America Treatment |
| url | http://www.sciencedirect.com/science/article/pii/S2772613423000264 |
| work_keys_str_mv | AT manuelfugartegil systemiclupuserythematosusinlatinamericaoutcomesandtherapeuticchallenges AT gracielasalarcon systemiclupuserythematosusinlatinamericaoutcomesandtherapeuticchallenges |