Osteoporosis Preclinical Research: A Systematic Review on Comparative Studies Using Ovariectomized Sheep

Osteoporosis Preclinical Research: A Systematic Review on Comparative Studies Using Ovariectomized Sheep

Sheep ovariectomy (OVX) alone or associated to steroid therapy, deficient diet, or hypothalamic–pituitary disconnection has proven to be of critical importance for osteoporosis research in orthopedics. However, the impact of specific variables, such as breed, age, diet, time after OVX, and other var...

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Bibliographic Details
Main Authors: Francesca Salamanna, Deyanira Contartese, Francesca Veronesi, Lucia Martini, Milena Fini
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
osteoporosis
ovariectomy
bone remodeling
sheep
systematic review
Online Access:https://www.mdpi.com/1422-0067/23/16/8904

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