Direct measurement of the mechanical work during translocation by the ribosome

Direct measurement of the mechanical work during translocation by the ribosome

A detailed understanding of tRNA/mRNA translocation requires measurement of the forces generated by the ribosome during this movement. Such measurements have so far remained elusive and, thus, little is known about the relation between force and translocation and how this reflects on its mechanism a...

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Bibliographic Details
Main Authors: Tingting Liu, Ariel Kaplan, Lisa Alexander, Shannon Yan, Jin-Der Wen, Laura Lancaster, Charles E Wickersham, Kurt Fredrick, Harry Noller, Ignacio Tinoco Jr, Carlos J Bustamante
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-08-01
Series:eLife
Subjects:
translation
ribosome
optical tweezer
single molecule
mechanical force
Online Access:https://elifesciences.org/articles/03406

Internet

https://elifesciences.org/articles/03406

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