Oral delivery of bi-autoantigens by bacterium-like particles (BLPs) against autoimmune diabetes in NOD mice

Oral delivery of bi-autoantigens by bacterium-like particles (BLPs) against autoimmune diabetes in NOD mice

AbstractInduction of oral tolerance by vaccination with type 1 diabetes mellitus (T1DM)-associated autoantigens exhibits great potential in preventing and treating this autoimmune disease. However, antigen degradation in the gastrointestinal tract (GIT) limits the delivery efficiency of oral antigen...

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Bibliographic Details
Main Authors:	Ruifeng Mao, Jin Wang, Ying Xu, Yuqi Wang, Mengmeng Wu, Lixia Mao, Yingying Chen, Dengchao Li, Tong Zhang, Enjie Diao, Zhenjing Chi, Yefu Wang, Xin Chang
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2023-12-01
Series:	Drug Delivery
Subjects:	Type 1 diabetes mellitus immune tolerance autoantigen bacterium-like particles oral vaccination
Online Access:	https://www.tandfonline.com/doi/10.1080/10717544.2023.2173339

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