MAPK1 promotes the metastasis and invasion of gastric cancer as a bidirectional transcription factor

MAPK1 promotes the metastasis and invasion of gastric cancer as a bidirectional transcription factor

Abstract Background The Mitogen-activated protein kinase 1 (MAPK1) has both independent functions of phosphorylating histones as a kinase and directly binding the promoter regions of genes to regulate gene expression as a transcription factor. Previous studies have identified elevated expression of...

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Bibliographic Details
Main Authors: Yue Wang, Zheng Guo, Yueli Tian, Liang Cong, Yulu Zheng, Zhiyuan Wu, Guangle Shan, Yao Xia, Yahong Zhu, Xingang Li, Ying Song
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Cancer
Subjects:
Gastric cancer
MAPK1
Bidirectional transcription factor
Cancer progression
Online Access:https://doi.org/10.1186/s12885-023-11480-3

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