Sex-specific regulation of IL-10 production in human adipose tissue in obesity

Sex-specific regulation of IL-10 production in human adipose tissue in obesity

BackgroundObesity-associated metabolic complications display sexual dimorphism and can be impacted by cytokines. We previously showed that interleukin-10 (IL-10) was upregulated in white adipose tissue (WAT) of obese women with type 2 diabetes (T2D). Whether this pertains to men is unknown. The aim...

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Bibliographic Details
Main Authors: Narmadha Subramanian, Beatriz Tavira, Kaisa Hofwimmer, Beate Gutsmann, Lucas Massier, Julie Abildgaard, Anders Juul, Mikael Rydén, Peter Arner, Jurga Laurencikiene
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Endocrinology
Subjects:
IL-10
sex-specific
adipose
macrophages
obesity
women
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.996954/full

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