Histone H3 phospho-regulation by KimH3 in both interphase and mitosis

Summary: Histone H3 is phosphorylated at Ser10 by multiple kinases, and many of them are anti-cancer targets. Here, we report the first kinase that can phosphorylate H3Ser10 in both interphase and mitosis, which we named KimH3 (kinase of interphase and mitotic Histone H3). Meta-analysis indicates th...

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Bibliographic Details
Main Authors: Junjun Wang, Xiaofei Tian, Chuanlin Feng, Chao Song, Biao Yu, Ying Wang, Xinmiao Ji, Xin Zhang
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223004492