Vitamin D supplementation compared to placebo in people with First Episode psychosis - Neuroprotection Design (DFEND): a protocol for a randomised, double-blind, placebo-controlled, parallel-group trial

Vitamin D supplementation compared to placebo in people with First Episode psychosis - Neuroprotection Design (DFEND): a protocol for a randomised, double-blind, placebo-controlled, parallel-group trial

Abstract Background People experiencing their first episode of psychosis are often deficient in vitamin D. Observational studies have reported an association between low vitamin D concentrations and poorer subsequent health outcomes in psychosis. A vitamin D deficiency in neonates and children has b...

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Bibliographic Details
Main Authors: Fiona Gaughran, Dominic Stringer, Michael Berk, Shubulade Smith, David Taylor, Eromona Whiskey, Sabine Landau, Robin Murray, Philip McGuire, Poonam Gardner-Sood, Gabriella Wojewodka, Simone Ciufolini, Harriet Jordan, Jessie Clarke, Lauren Allen, Amir Krivoy, Brendon Stubbs, Philippa Lowe, Maurice Arbuthnott, Shanaya Rathod, Andrew Boardman, Mudasir Firdosi, John J. McGrath
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Trials
Subjects:
Psychosis
First episode
Vitamin D
25OHD
Randomised controlled trial
Positive and Negative Syndrome Scale
Online Access:https://doi.org/10.1186/s13063-019-3758-9

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