Calcium Sulfate as Bone Graft Substitute in the Treatment of Osseous Bone Defects, A Prospective Study
Background: Calcium sulfate belongs to synthetic ceramic group of bone graft substitutes having an osteoconductive property. Calcium sulfate is an easily available, economic bone graft substitute. It is a bio-inert material which over a period of weeks get resorbed and fibrovascular tissue takes...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2013-12-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/3791/74-%206404_E(Var)_F(DK)_PF1(SH_Pr_P)_PFA(H)_PF1(RPP)_PF2(PS).pdf |
| Summary: | Background: Calcium sulfate belongs to synthetic ceramic
group of bone graft substitutes having an osteoconductive
property. Calcium sulfate is an easily available, economic bone
graft substitute. It is a bio-inert material which over a period
of weeks get resorbed and fibrovascular tissue takes its place
which eventually allows neovascularisation and bone formation
within the area. Use of calcium sulfate as a bone graft substitutes
avoids the complications and morbidity associated with autograft
like infection, second surgery, and finite amount of graft.
Material and Methods: A total of 15 patients with benign
bone lesions and chronic osteomyelitis were operated and the
osseous defects were filled with calcium sulfate which was
comprehensively sterilized .Patients were followed with serial
radiographs at six week intervals. Calcium sulfate resorption and
new bone formation was studied.
Results: Thirteen cases out of 15 showed calcium sulphate
resorption and new bone incorporation. Calcaium sulphate
resorption occurred at an average of 14.5 weeks (range,13-
18weeks) whereas new bone incorporation occurred at an
average of 6months ( range,5-7months). Thirteen patients out of
these 15 cases returned to full activities of daily living. One patient
had pathological fracture at the osseous defect postoperatively.
One patient with GCT of distal end of tibia had recurrence of
tumor and had to undergo second surgery.
Conclusion: Although autogenous bone graft is the gold
standard for bone grafting, it has limitations like finite amount,
additional surgery and donor site morbidity. Calcium sulphate
is safe, efficient and easily available bone graft substitute in
the treatment of osseous defects. Most common complication
encountered was aseptic serous discharge. Functional results
were favorable in most of the cases. |
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| ISSN: | 2249-782X 0973-709X |