Clinical Features and Treatment of Fibrous Histiocytomas of the Tongue: A Systematic Review
Abstract Introduction Benign fibrous histiocytomas are common lesions of the skin that rarely affect the tongue. Such cases are available in the literature exclusively as case reports. Similarly, malignant fibrous histiocytoma, now classified as undifferentiated pleomorphic sarcoma, is...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Thieme Revinter Publicações Ltda.
2018-01-01
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| Series: | International Archives of Otorhinolaryngology |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1602819 |
| _version_ | 1818494634128572416 |
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| author | Austin Nguyen Adam Vaudreuil Paul Haun Gabriel Caponetti Christopher Huerter |
| author_facet | Austin Nguyen Adam Vaudreuil Paul Haun Gabriel Caponetti Christopher Huerter |
| author_sort | Austin Nguyen |
| collection | DOAJ |
| description | Abstract
Introduction Benign fibrous histiocytomas are common lesions of the skin that rarely affect the tongue. Such cases are available in the literature exclusively as case reports. Similarly, malignant fibrous histiocytoma, now classified as undifferentiated pleomorphic sarcoma, is exceedingly rare in the tongue and not fully understood.
Objectives This study systematically reviews the available literature discussing the clinical and pathological features of malignant and benign fibrous histiocytomas.
Data Synthesis A total of 20 cases were included in this review. Patient-level data were extracted from cases to include clinical presentation, workup, treatment, and outcome.
Conclusion Benign fibrous histiocytomas are consistent in clinical and histopathologic presentation. Surgical treatment provides excellent outcome, with no recurrence in all excised cases. Malignant tumors have a more aggressive clinical and pathological presentation. Surgical treatment with possible adjuvant radiotherapy resulted in recurrence in 40% of cases (follow-up of 24 months), and death due to disease in 47% of patients (follow-up of 19 months). |
| first_indexed | 2024-12-10T18:09:10Z |
| format | Article |
| id | doaj.art-981a637106934fd0aa2ac58b6b87e7d5 |
| institution | Directory Open Access Journal |
| issn | 1809-9777 1809-4864 |
| language | English |
| last_indexed | 2024-12-10T18:09:10Z |
| publishDate | 2018-01-01 |
| publisher | Thieme Revinter Publicações Ltda. |
| record_format | Article |
| series | International Archives of Otorhinolaryngology |
| spelling | doaj.art-981a637106934fd0aa2ac58b6b87e7d52022-12-22T01:38:32ZengThieme Revinter Publicações Ltda.International Archives of Otorhinolaryngology1809-97771809-48642018-01-01220109410210.1055/s-0037-1602819Clinical Features and Treatment of Fibrous Histiocytomas of the Tongue: A Systematic ReviewAustin Nguyen0Adam Vaudreuil1Paul Haun2Gabriel Caponetti3Christopher Huerter4Division of Dermatology, Creighton University School of Medicine, Omaha, Nebraska, United StatesDivision of Dermatology, Creighton University School of Medicine, Omaha, Nebraska, United StatesDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United StatesDepartment of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United StatesDivision of Dermatology, Creighton University School of Medicine, Omaha, Nebraska, United StatesAbstract Introduction Benign fibrous histiocytomas are common lesions of the skin that rarely affect the tongue. Such cases are available in the literature exclusively as case reports. Similarly, malignant fibrous histiocytoma, now classified as undifferentiated pleomorphic sarcoma, is exceedingly rare in the tongue and not fully understood. Objectives This study systematically reviews the available literature discussing the clinical and pathological features of malignant and benign fibrous histiocytomas. Data Synthesis A total of 20 cases were included in this review. Patient-level data were extracted from cases to include clinical presentation, workup, treatment, and outcome. Conclusion Benign fibrous histiocytomas are consistent in clinical and histopathologic presentation. Surgical treatment provides excellent outcome, with no recurrence in all excised cases. Malignant tumors have a more aggressive clinical and pathological presentation. Surgical treatment with possible adjuvant radiotherapy resulted in recurrence in 40% of cases (follow-up of 24 months), and death due to disease in 47% of patients (follow-up of 19 months).http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1602819dermatofibrosarcomadermatofibromafibrous histiocytomatongue neoplasm |
| spellingShingle | Austin Nguyen Adam Vaudreuil Paul Haun Gabriel Caponetti Christopher Huerter Clinical Features and Treatment of Fibrous Histiocytomas of the Tongue: A Systematic Review International Archives of Otorhinolaryngology dermatofibrosarcoma dermatofibroma fibrous histiocytoma tongue neoplasm |
| title | Clinical Features and Treatment of Fibrous Histiocytomas of the Tongue: A Systematic Review |
| title_full | Clinical Features and Treatment of Fibrous Histiocytomas of the Tongue: A Systematic Review |
| title_fullStr | Clinical Features and Treatment of Fibrous Histiocytomas of the Tongue: A Systematic Review |
| title_full_unstemmed | Clinical Features and Treatment of Fibrous Histiocytomas of the Tongue: A Systematic Review |
| title_short | Clinical Features and Treatment of Fibrous Histiocytomas of the Tongue: A Systematic Review |
| title_sort | clinical features and treatment of fibrous histiocytomas of the tongue a systematic review |
| topic | dermatofibrosarcoma dermatofibroma fibrous histiocytoma tongue neoplasm |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1602819 |
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