Bioinformatics and Functional Assessment of Toxin-Antitoxin Systems in <i>Staphylococcus aureus</i>

Bioinformatics and Functional Assessment of Toxin-Antitoxin Systems in <i>Staphylococcus aureus</i>

<i>Staphylococcus aureus</i> is a nosocomial pathogen that can cause chronic to persistent infections. Among different mediators of pathogenesis, toxin-antitoxin (TA) systems are emerging as the most prominent. These systems are frequently studied in <i>Escherichia coli</i> a...

Full description

Bibliographic Details
Main Authors:	Gul Habib, Qing Zhu, Baolin Sun
Format:	Article
Language:	English
Published:	MDPI AG 2018-11-01
Series:	Toxins
Subjects:	<i>Staphylococcus aureus</i> toxin-antitoxin systems HigBA pathogenicity islands
Online Access:	https://www.mdpi.com/2072-6651/10/11/473

Similar Items

The higBA Toxin-Antitoxin Module From the Opportunistic Pathogen Acinetobacter baumannii – Regulation, Activity, and Evolution
by: Julija Armalytė, et al.
Published: (2018-04-01)

HigB1 Toxin in Mycobacterium tuberculosis Is Upregulated During Stress and Required to Establish Infection in Guinea Pigs
by: Arun Sharma, et al.
Published: (2021-11-01)

<i>Pseudomonas putida</i> Responds to the Toxin GraT by Inducing Ribosome Biogenesis Factors and Repressing TCA Cycle Enzymes
by: Andres Ainelo, et al.
Published: (2019-02-01)

The Disordered <i>C</i>-Terminus of the Chaperone DnaK Increases the Competitive Fitness of <i>Pseudomonas putida</i> and Facilitates the Toxicity of GraT
by: Sirli Rosendahl, et al.
Published: (2021-02-01)

Impacts of the Type I Toxin–Antitoxin System, SprG1/SprF1, on <em>Staphylococcus aureus</em> Gene Expression
by: Kinga Chlebicka, et al.
Published: (2021-05-01)

Genome mining reveals the prevalence and extensive diversity of toxin–antitoxin systems in Staphylococcus aureus
by: Jie Xu, et al.
Published: (2023-05-01)

A novel type I toxin-antitoxin system modulates persister cell formation in Staphylococcus aureus
by: Gul Habib, et al.
Published: (2020-02-01)

Structural Insights Into the Transcriptional Regulation of HigBA Toxin–Antitoxin System by Antitoxin HigA in Pseudomonas aeruginosa
by: Ying Liu, et al.
Published: (2020-01-01)

Toxin antitoxin system as an antimicrobial target for antibiotic resistant staphylococcus aureus
by: Ghafouryan, Sobhan
Published: (2014)

<i>Staphylococcus aureus</i> Toxins: An Update on Their Pathogenic Properties and Potential Treatments
by: Nour Ahmad-Mansour, et al.
Published: (2021-09-01)

YjbH Solubility Controls Spx in Staphylococcus aureus: Implication for MazEF Toxin-Antitoxin System Regulation
by: Olesya O. Panasenko, et al.
Published: (2020-02-01)

Type I Toxin-Antitoxin Systems in Clostridia
by: Olga Soutourina
Published: (2019-05-01)

Applications of toxin-antitoxin systems in synthetic biology
by: Jianzhong Lin, et al.
Published: (2023-06-01)

Correlation between <i>mazEF</i> Toxin-Antitoxin System Expression and Methicillin Susceptibility in <i>Staphylococcus aureus</i> and Its Relation to Biofilm-Formation
by: Aya Abd El rahman, et al.
Published: (2021-10-01)

Toxin-Antitoxin Systems of Staphylococcus aureus
by: Christopher F. Schuster, et al.
Published: (2016-05-01)

Large-Scale Comparison of Toxin and Antitoxins in <i>Listeria monocytogenes</i>
by: José Antonio Agüero, et al.
Published: (2020-01-01)

Paeoniflorin Derivative in Paeoniae Radix Aqueous Extract Suppresses Alpha-Toxin of Staphylococcus aureus
by: Xiaoye Liu, et al.
Published: (2021-03-01)

The Toxin-Antitoxin MazEF Drives <named-content content-type="genus-species">Staphylococcus aureus</named-content> Biofilm Formation, Antibiotic Tolerance, and Chronic Infection
by: Dongzhu Ma, et al.
Published: (2019-12-01)

sRNA Antitoxins: More than One Way to Repress a Toxin
by: Jia Wen, et al.
Published: (2014-08-01)

Identification of a Toxin–Antitoxin System That Contributes to Persister Formation by Reducing NAD in <i>Pseudomonas aeruginosa</i>
by: Jingyi Zhou, et al.
Published: (2021-04-01)

The Toxin-Antitoxin Systems of the Opportunistic Pathogen <i>Stenotrophomonas maltophilia</i> of Environmental and Clinical Origin
by: Laurita Klimkaitė, et al.
Published: (2020-10-01)

Toxin-Antitoxin Systems in Clinical Pathogens
by: Laura Fernández-García, et al.
Published: (2016-07-01)

In Silico Characterization of Toxin-Antitoxin Systems in <i>Campylobacter</i> Isolates Recovered from Food Sources and Sporadic Human Illness
by: Bishoy Wadie, et al.
Published: (2021-01-01)

An Eye on <i>Staphylococcus aureus</i> Toxins: Roles in Ocular Damage and Inflammation
by: Roger Astley, et al.
Published: (2019-06-01)

HigB Reciprocally Controls Biofilm Formation and the Expression of Type III Secretion System Genes through Influencing the Intracellular c-di-GMP Level in <i>Pseudomonas aeruginosa</i>
by: Yueying Zhang, et al.
Published: (2018-10-01)

A Primary Physiological Role of Toxin/Antitoxin Systems Is Phage Inhibition
by: Sooyeon Song, et al.
Published: (2020-08-01)

Type II Toxin–Antitoxin Systems in <i>Pseudomonas aeruginosa</i>
by: Meng Li, et al.
Published: (2023-02-01)

Quorum Sensing and Toxin Production in <i>Staphylococcus aureus</i> Osteomyelitis: Pathogenesis and Paradox
by: Casey E. Butrico, et al.
Published: (2020-08-01)

Epidemiological and Clinical Evidence for the Role of Toxins in <i>S. aureus</i> Human Disease
by: Monique R. Bennett, et al.
Published: (2020-06-01)

Characterization of Two Toxin-Antitoxin Systems in Deep-Sea <i>Streptomyces</i> sp. SCSIO 02999
by: Waner Zhan, et al.
Published: (2019-04-01)

<i>In Silico</i> Analysis of Genetic VapC Profiles from the Toxin-Antitoxin Type II VapBC Modules among Pathogenic, Intermediate, and Non-Pathogenic <i>Leptospira</i>
by: Alexandre P. Y. Lopes, et al.
Published: (2019-02-01)

Multiple Toxin-Antitoxin Systems in Mycobacterium tuberculosis
by: Ambre Sala, et al.
Published: (2014-03-01)

<i>Staphylococcus aureus</i> Extracellular Vesicles: A Story of Toxicity and the Stress of 2020
by: Xiaogang Wang, et al.
Published: (2021-01-01)

Molecular and Structural Basis of Cross-Reactivity in <i>M. tuberculosis</i> Toxin–Antitoxin Systems
by: Himani Tandon, et al.
Published: (2020-07-01)

The Role of <i>Staphylococcus aureus</i> and Its Toxins in the Pathogenesis of Allergic Asthma
by: Ilka Jorde, et al.
Published: (2022-12-01)

Type II Toxin-Antitoxin Systems and Persister Cells
by: David W. Holden, et al.
Published: (2018-11-01)

Influence of Magnolol on the Secretion of α-Toxin by Staphylococcus aureus
by: Xu-Ming Deng, et al.
Published: (2010-03-01)

Genome Sequencing of five <i>Lacticaseibacillus</i> Strains and Analysis of Type I and II Toxin-Antitoxin System Distribution
by: Alessia Levante, et al.
Published: (2021-03-01)

Machine Learning with Alpha Toxin Phenotype to Predict Clinical Outcome in Patients with <i>Staphylococcus aureus</i> Bloodstream Infection
by: Brent Beadell, et al.
Published: (2023-06-01)

Reply to Holden and Errington, “Type II Toxin-Antitoxin Systems and Persister Cells”
by: Frédéric Goormaghtigh, et al.
Published: (2018-11-01)