BDNF blood serum linkage with BDNF gene polymorphism (rs6265) in thyroid pathology patients in the West-Ukrainian population
Objective. Brain-derived neurotrophic factor (BDNF) is identified as an important growth factor involved in learning and memory. Patients with Hashimoto’s thyroiditis can suffer from cognitive dysfunction, whereas BDNF is directly regulated by thyroid hormones. It seems reasonable to propose that ch...
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Format: | Article |
Language: | English |
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Sciendo
2021-10-01
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Series: | Endocrine Regulations |
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Online Access: | https://doi.org/10.2478/enr-2021-0021 |
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author | Kamyshna Iryna I. Pavlovych Larysa B. Sydorchuk Larysa P. Malyk Igor V. Kamyshnyi Aleksandr M. |
author_facet | Kamyshna Iryna I. Pavlovych Larysa B. Sydorchuk Larysa P. Malyk Igor V. Kamyshnyi Aleksandr M. |
author_sort | Kamyshna Iryna I. |
collection | DOAJ |
description | Objective. Brain-derived neurotrophic factor (BDNF) is identified as an important growth factor involved in learning and memory. Patients with Hashimoto’s thyroiditis can suffer from cognitive dysfunction, whereas BDNF is directly regulated by thyroid hormones. It seems reasonable to propose that changes in BDNF expression underlie some of the persistent neurological impairments associated with hypothyroidism. |
first_indexed | 2024-12-18T02:52:13Z |
format | Article |
id | doaj.art-981cc89305db42a2ae61d9859ecc69f2 |
institution | Directory Open Access Journal |
issn | 1336-0329 |
language | English |
last_indexed | 2024-12-18T02:52:13Z |
publishDate | 2021-10-01 |
publisher | Sciendo |
record_format | Article |
series | Endocrine Regulations |
spelling | doaj.art-981cc89305db42a2ae61d9859ecc69f22022-12-21T21:23:25ZengSciendoEndocrine Regulations1336-03292021-10-0155419320310.2478/enr-2021-0021BDNF blood serum linkage with BDNF gene polymorphism (rs6265) in thyroid pathology patients in the West-Ukrainian populationKamyshna Iryna I.0Pavlovych Larysa B.1Sydorchuk Larysa P.2Malyk Igor V.3Kamyshnyi Aleksandr M.4I. Horbachevsky Ternopil National Medical University, UkraineHSEEU “Bukovinian State Medical University”, Chernivtsi, UkraineHSEEU “Bukovinian State Medical University”, Chernivtsi, UkraineYuriy Fedkovych Chernivtsi National University, UkraineI. Horbachevsky Ternopil National Medical University, UkraineObjective. Brain-derived neurotrophic factor (BDNF) is identified as an important growth factor involved in learning and memory. Patients with Hashimoto’s thyroiditis can suffer from cognitive dysfunction, whereas BDNF is directly regulated by thyroid hormones. It seems reasonable to propose that changes in BDNF expression underlie some of the persistent neurological impairments associated with hypothyroidism.https://doi.org/10.2478/enr-2021-0021bdnfautoimmune thyroiditishypothyroidism |
spellingShingle | Kamyshna Iryna I. Pavlovych Larysa B. Sydorchuk Larysa P. Malyk Igor V. Kamyshnyi Aleksandr M. BDNF blood serum linkage with BDNF gene polymorphism (rs6265) in thyroid pathology patients in the West-Ukrainian population Endocrine Regulations bdnf autoimmune thyroiditis hypothyroidism |
title | BDNF blood serum linkage with BDNF gene polymorphism (rs6265) in thyroid pathology patients in the West-Ukrainian population |
title_full | BDNF blood serum linkage with BDNF gene polymorphism (rs6265) in thyroid pathology patients in the West-Ukrainian population |
title_fullStr | BDNF blood serum linkage with BDNF gene polymorphism (rs6265) in thyroid pathology patients in the West-Ukrainian population |
title_full_unstemmed | BDNF blood serum linkage with BDNF gene polymorphism (rs6265) in thyroid pathology patients in the West-Ukrainian population |
title_short | BDNF blood serum linkage with BDNF gene polymorphism (rs6265) in thyroid pathology patients in the West-Ukrainian population |
title_sort | bdnf blood serum linkage with bdnf gene polymorphism rs6265 in thyroid pathology patients in the west ukrainian population |
topic | bdnf autoimmune thyroiditis hypothyroidism |
url | https://doi.org/10.2478/enr-2021-0021 |
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