Brain inflammation in a chronic epilepsy model: Evolving pattern of the translocator protein during epileptogenesis

Brain inflammation in a chronic epilepsy model: Evolving pattern of the translocator protein during epileptogenesis

Aims: A hallmark in the neuropathology of temporal lobe epilepsy is brain inflammation which has been suggested as both a biomarker and a new mechanistic target for treatments. The translocator protein (TSPO), due to its high upregulation under neuroinflammatory conditions and the availability of se...

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Bibliographic Details
Main Authors: Halima Amhaoul, Julie Hamaide, Daniele Bertoglio, Stephanie Nadine Reichel, Jeroen Verhaeghe, Elly Geerts, Debby Van Dam, Peter Paul De Deyn, Samir Kumar-Singh, Andrew Katsifis, Annemie Van Der Linden, Steven Staelens, Stefanie Dedeurwaerdere
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Neurobiology of Disease
Subjects:
Epilepsy
Seizure
Brain- and neuroinflammation
Translocator protein or peripheral benzodiazepine receptor
Microglia
18F-PBR111 PET
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115300516

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