Association between admission albumin levels and 30-day readmission after hip fracture surgery in geriatric patients: a propensity score-matched study
Abstract Purpose This study aimed to evaluate the correlation admission albumin levels and 30-day readmission after hip fracture surgery in geriatric patients. Methods In this retrospective cohort study, 1270 geriatric patients admitted for hip fractures to a level I trauma center were included. Pat...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-03-01
|
| Series: | BMC Musculoskeletal Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12891-024-07336-x |
| _version_ | 1797233908038762496 |
|---|---|
| author | Wanyun Tang Wei Yao Wei Wang Wenbo Ding Xiaomin Ni RenJian He |
| author_facet | Wanyun Tang Wei Yao Wei Wang Wenbo Ding Xiaomin Ni RenJian He |
| author_sort | Wanyun Tang |
| collection | DOAJ |
| description | Abstract Purpose This study aimed to evaluate the correlation admission albumin levels and 30-day readmission after hip fracture surgery in geriatric patients. Methods In this retrospective cohort study, 1270 geriatric patients admitted for hip fractures to a level I trauma center were included. Patients were stratified by clinical thresholds and albumin level quartiles. The association between admission albumin levels and 30-day readmission risk was assessed using multivariate logistic regression and propensity score-matched analyses. The predictive accuracy of albumin levels for readmission was evaluated by ROC curves. The dose–response relationship between albumin levels and readmission risk was examined. Results The incidence of 30-day readmission was significantly higher among hypoalbuminemia patients than those with normal albumin levels (OR = 2.090, 95%CI:1.296–3.370, p = 0.003). Furthermore, propensity score-matched analyses demonstrated that patients in the Q2(35.0–37.9 g/L) (OR 0.621, 95%CI 0.370–1.041, p = 0.070), Q3(38.0–40.9 g/L) (OR 0.378, 95%CI 0.199–0.717, p < 0.001) and Q4 (≥ 41 g/L) (OR 0.465, 95%CI 0.211–0.859, p = 0.047) quartiles had a significantly lower risk of 30-day readmission compared to those in the Q1(< 35 g/L) quartile. These associations remained significant after propensity score matching (PSM) and subgroup analyses. Dose–response relationships between albumin levels and 30-day readmission were observed. Conclusions Lower admission albumin levels were independently associated with higher 30-day readmission rates in elderly hip fracture patients. Our findings indicate that serum albumin may assist perioperative risk assessment, and prompt correction of hypoalbuminemia and malnutrition could reduce short-term readmissions after hip fracture surgery in this high-risk population. |
| first_indexed | 2024-04-24T16:23:38Z |
| format | Article |
| id | doaj.art-981f13bac7c44550a493e0c91d0484a2 |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-04-24T16:23:38Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-981f13bac7c44550a493e0c91d0484a22024-03-31T11:06:13ZengBMCBMC Musculoskeletal Disorders1471-24742024-03-0125111210.1186/s12891-024-07336-xAssociation between admission albumin levels and 30-day readmission after hip fracture surgery in geriatric patients: a propensity score-matched studyWanyun Tang0Wei Yao1Wei Wang2Wenbo Ding3Xiaomin Ni4RenJian He5Department of Orthopedics, Zigong First People’s HospitalDepartment of Orthopedics, Dandong Central Hospital, China Medical UniversityDepartment of Orthopedics, Dandong Central Hospital, China Medical UniversityDepartment of Orthopedics, Dandong Central Hospital, China Medical UniversityDepartment of Orthopedics, Zigong Fourth People’s HospitalDepartment of Orthopedics, Zigong First People’s HospitalAbstract Purpose This study aimed to evaluate the correlation admission albumin levels and 30-day readmission after hip fracture surgery in geriatric patients. Methods In this retrospective cohort study, 1270 geriatric patients admitted for hip fractures to a level I trauma center were included. Patients were stratified by clinical thresholds and albumin level quartiles. The association between admission albumin levels and 30-day readmission risk was assessed using multivariate logistic regression and propensity score-matched analyses. The predictive accuracy of albumin levels for readmission was evaluated by ROC curves. The dose–response relationship between albumin levels and readmission risk was examined. Results The incidence of 30-day readmission was significantly higher among hypoalbuminemia patients than those with normal albumin levels (OR = 2.090, 95%CI:1.296–3.370, p = 0.003). Furthermore, propensity score-matched analyses demonstrated that patients in the Q2(35.0–37.9 g/L) (OR 0.621, 95%CI 0.370–1.041, p = 0.070), Q3(38.0–40.9 g/L) (OR 0.378, 95%CI 0.199–0.717, p < 0.001) and Q4 (≥ 41 g/L) (OR 0.465, 95%CI 0.211–0.859, p = 0.047) quartiles had a significantly lower risk of 30-day readmission compared to those in the Q1(< 35 g/L) quartile. These associations remained significant after propensity score matching (PSM) and subgroup analyses. Dose–response relationships between albumin levels and 30-day readmission were observed. Conclusions Lower admission albumin levels were independently associated with higher 30-day readmission rates in elderly hip fracture patients. Our findings indicate that serum albumin may assist perioperative risk assessment, and prompt correction of hypoalbuminemia and malnutrition could reduce short-term readmissions after hip fracture surgery in this high-risk population.https://doi.org/10.1186/s12891-024-07336-xHip fracturePneumoniaHypoalbuminemiaRisk factorGeriatric |
| spellingShingle | Wanyun Tang Wei Yao Wei Wang Wenbo Ding Xiaomin Ni RenJian He Association between admission albumin levels and 30-day readmission after hip fracture surgery in geriatric patients: a propensity score-matched study BMC Musculoskeletal Disorders Hip fracture Pneumonia Hypoalbuminemia Risk factor Geriatric |
| title | Association between admission albumin levels and 30-day readmission after hip fracture surgery in geriatric patients: a propensity score-matched study |
| title_full | Association between admission albumin levels and 30-day readmission after hip fracture surgery in geriatric patients: a propensity score-matched study |
| title_fullStr | Association between admission albumin levels and 30-day readmission after hip fracture surgery in geriatric patients: a propensity score-matched study |
| title_full_unstemmed | Association between admission albumin levels and 30-day readmission after hip fracture surgery in geriatric patients: a propensity score-matched study |
| title_short | Association between admission albumin levels and 30-day readmission after hip fracture surgery in geriatric patients: a propensity score-matched study |
| title_sort | association between admission albumin levels and 30 day readmission after hip fracture surgery in geriatric patients a propensity score matched study |
| topic | Hip fracture Pneumonia Hypoalbuminemia Risk factor Geriatric |
| url | https://doi.org/10.1186/s12891-024-07336-x |
| work_keys_str_mv | AT wanyuntang associationbetweenadmissionalbuminlevelsand30dayreadmissionafterhipfracturesurgeryingeriatricpatientsapropensityscorematchedstudy AT weiyao associationbetweenadmissionalbuminlevelsand30dayreadmissionafterhipfracturesurgeryingeriatricpatientsapropensityscorematchedstudy AT weiwang associationbetweenadmissionalbuminlevelsand30dayreadmissionafterhipfracturesurgeryingeriatricpatientsapropensityscorematchedstudy AT wenboding associationbetweenadmissionalbuminlevelsand30dayreadmissionafterhipfracturesurgeryingeriatricpatientsapropensityscorematchedstudy AT xiaominni associationbetweenadmissionalbuminlevelsand30dayreadmissionafterhipfracturesurgeryingeriatricpatientsapropensityscorematchedstudy AT renjianhe associationbetweenadmissionalbuminlevelsand30dayreadmissionafterhipfracturesurgeryingeriatricpatientsapropensityscorematchedstudy |