IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME

The results of correction of immune status in patients with pyo-necrotic forms of diabetic foot are presented. It is established that the clinical signs of secondary immune deficiency in patients with pyo-necrotic forms of diabetic foot are accompanied by changes in laboratory immunological paramete...

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Main Authors: R. V. Eselevich, A. N. Lipin, N. V. Ruhlyada, I. A. Solovyev
Format: Article
Language:Russian
Published: Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” 2015-06-01
Series:Кубанский научный медицинский вестник
Subjects:
Online Access:https://ksma.elpub.ru/jour/article/view/326
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author R. V. Eselevich
A. N. Lipin
N. V. Ruhlyada
I. A. Solovyev
author_facet R. V. Eselevich
A. N. Lipin
N. V. Ruhlyada
I. A. Solovyev
author_sort R. V. Eselevich
collection DOAJ
description The results of correction of immune status in patients with pyo-necrotic forms of diabetic foot are presented. It is established that the clinical signs of secondary immune deficiency in patients with pyo-necrotic forms of diabetic foot are accompanied by changes in laboratory immunological parameters: the presence of relative and absolute lymphopenia; reduction in the relative and absolute T-lymphocyte numbers, and of subpopulations of CD4 lymphocytes, as well as levels of phagocytosis. The data presented indicates that inclusion of immunomodulators into the treatment program in patients with pyo-necrotic forms of diabetic foot led to a reduction in treatment time, complications, and to positive changes in the parameters characterizing the state of the immune system.
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publishDate 2015-06-01
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spelling doaj.art-981f8088ba114ef19e9978ecda1fd5e92024-02-25T10:57:16ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442015-06-013495410.25207/1608-6228-2015-3-49-54326IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROMER. V. Eselevich0A. N. Lipin1N. V. Ruhlyada2I. A. Solovyev3Kirov Military medical academyKirov Military medical academyKirov Military medical academyKirov Military medical academyThe results of correction of immune status in patients with pyo-necrotic forms of diabetic foot are presented. It is established that the clinical signs of secondary immune deficiency in patients with pyo-necrotic forms of diabetic foot are accompanied by changes in laboratory immunological parameters: the presence of relative and absolute lymphopenia; reduction in the relative and absolute T-lymphocyte numbers, and of subpopulations of CD4 lymphocytes, as well as levels of phagocytosis. The data presented indicates that inclusion of immunomodulators into the treatment program in patients with pyo-necrotic forms of diabetic foot led to a reduction in treatment time, complications, and to positive changes in the parameters characterizing the state of the immune system.https://ksma.elpub.ru/jour/article/view/326сахарный диабетсиндром диабетической стопыдиабетическая гангренаиммунитетвторичная иммунная недостаточностьиммунокоррекциясиндром системной воспалительной реакциилечениеdiabetes mellitusdiabetic foot syndromediabetic gangreneimmunitysecondary immunodeficiencyimmunocorrectionsystemic inflammatory response syndrometreatment
spellingShingle R. V. Eselevich
A. N. Lipin
N. V. Ruhlyada
I. A. Solovyev
IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME
Кубанский научный медицинский вестник
сахарный диабет
синдром диабетической стопы
диабетическая гангрена
иммунитет
вторичная иммунная недостаточность
иммунокоррекция
синдром системной воспалительной реакции
лечение
diabetes mellitus
diabetic foot syndrome
diabetic gangrene
immunity
secondary immunodeficiency
immunocorrection
systemic inflammatory response syndrome
treatment
title IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME
title_full IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME
title_fullStr IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME
title_full_unstemmed IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME
title_short IMMUNOTROPIC THERAPY IN THE COMPLEX TREATMENT OF PATIENTS WITH DIABETIC FOOT SYNDROME
title_sort immunotropic therapy in the complex treatment of patients with diabetic foot syndrome
topic сахарный диабет
синдром диабетической стопы
диабетическая гангрена
иммунитет
вторичная иммунная недостаточность
иммунокоррекция
синдром системной воспалительной реакции
лечение
diabetes mellitus
diabetic foot syndrome
diabetic gangrene
immunity
secondary immunodeficiency
immunocorrection
systemic inflammatory response syndrome
treatment
url https://ksma.elpub.ru/jour/article/view/326
work_keys_str_mv AT rveselevich immunotropictherapyinthecomplextreatmentofpatientswithdiabeticfootsyndrome
AT anlipin immunotropictherapyinthecomplextreatmentofpatientswithdiabeticfootsyndrome
AT nvruhlyada immunotropictherapyinthecomplextreatmentofpatientswithdiabeticfootsyndrome
AT iasolovyev immunotropictherapyinthecomplextreatmentofpatientswithdiabeticfootsyndrome