Appropriateness and clinical outcomes of short sustained low-efficiency dialysis: A national experience
Sustained low-efficiency dialysis (SLED) is usually performed over 6–12 h among hemodynamically unstable patients. Conduction of 4-h SLED may spare time and manpower during hospitalization. Therefore, we conducted a retrospective observational study to explore the appropriateness and clinical outcom...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2023-12-01
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| Series: | Open Medicine |
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| Online Access: | https://doi.org/10.1515/med-2023-0868 |
| _version_ | 1797397426878808064 |
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| author | Rahhal Alaa Najim Mostafa Mahfouz Ahmed Habib Mhd Baraa Hassen Sara Seife Al-Shekh Isra’a Ahmed Ashraf Omer Toba Haneen Abbarh Shahem El Hassan Mawahib Al Yafei Sumaya Badr Amr Mahmoud Khaled Mohamed |
| author_facet | Rahhal Alaa Najim Mostafa Mahfouz Ahmed Habib Mhd Baraa Hassen Sara Seife Al-Shekh Isra’a Ahmed Ashraf Omer Toba Haneen Abbarh Shahem El Hassan Mawahib Al Yafei Sumaya Badr Amr Mahmoud Khaled Mohamed |
| author_sort | Rahhal Alaa |
| collection | DOAJ |
| description | Sustained low-efficiency dialysis (SLED) is usually performed over 6–12 h among hemodynamically unstable patients. Conduction of 4-h SLED may spare time and manpower during hospitalization. Therefore, we conducted a retrospective observational study to explore the appropriateness and clinical outcomes of 4-h SLED among critically ill patients admitted to our center from 1/06/2016 to 1/06/2020. Renal parameters including blood urea nitrogen, serum creatinine, sodium, phosphorus, potassium, and bicarbonate were determined on the day of dialysis before SLED and within 24 h after SLED, and clinical outcomes including, acute kidney injury (AKI) recovery, in-hospital mortality, 30-day mortality, 180-day mortality, and re-admission with AKI, were evaluated. Of the 304 patients included, 69.4% were male. The majority of patients were from the Middle East (65.8%), followed by 28.6% from Asia. Four-hour SLED resulted in a significant improvement in the renal parameters. Recovery from AKI was observed in 25.4%, in-hospital mortality rate was 48.7%, while the 30- and 180-day mortality outcomes were 3.2 and 9.6%, respectively, and re-admission with AKI was observed in 16.9%. Our findings suggest that 4-h SLED significantly improved renal parameters and was associated with favorable clinical outcomes in terms of survival and AKI recovery, suggesting possible utilization of SLED shorter than 6 h in the acute settings to preserve time and manpower for procedures. |
| first_indexed | 2024-03-09T01:09:47Z |
| format | Article |
| id | doaj.art-981fb7a9e37a4008a12f230ece3889e7 |
| institution | Directory Open Access Journal |
| issn | 2391-5463 |
| language | English |
| last_indexed | 2024-03-09T01:09:47Z |
| publishDate | 2023-12-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj.art-981fb7a9e37a4008a12f230ece3889e72023-12-11T07:36:35ZengDe GruyterOpen Medicine2391-54632023-12-011818810.1515/med-2023-0868Appropriateness and clinical outcomes of short sustained low-efficiency dialysis: A national experienceRahhal Alaa0Najim Mostafa1Mahfouz Ahmed2Habib Mhd Baraa3Hassen Sara Seife4Al-Shekh Isra’a5Ahmed Ashraf Omer6Toba Haneen7Abbarh Shahem8El Hassan Mawahib9Al Yafei Sumaya10Badr Amr11Mahmoud Khaled Mohamed12Pharmacy Department, Hamad Medical Corporation, Doha, QatarInternal Medicine Department, Rochester Regional Health – Unity Hospital, New York, USAPharmacy Department, Hamad Medical Corporation, Doha, QatarInternal Medicine Department, Hamad Medical Corporation, Doha, QatarInternal Medicine Department, Hamad Medical Corporation, Doha, QatarInternal Medicine Department, Hamad Medical Corporation, Doha, QatarInternal Medicine Department, Hamad Medical Corporation, Doha, QatarInternal Medicine Department, Hamad Medical Corporation, Doha, QatarInternal Medicine Department, Hamad Medical Corporation, Doha, QatarCritical Care Department, Hamad Medical Corporation, Doha, QatarPharmacy Department, Hamad Medical Corporation, Doha, QatarHeart Failure Department, Hamad Medical Corporation, Doha, QatarNephology Department, Hamad Medical Corporation, Doha, QatarSustained low-efficiency dialysis (SLED) is usually performed over 6–12 h among hemodynamically unstable patients. Conduction of 4-h SLED may spare time and manpower during hospitalization. Therefore, we conducted a retrospective observational study to explore the appropriateness and clinical outcomes of 4-h SLED among critically ill patients admitted to our center from 1/06/2016 to 1/06/2020. Renal parameters including blood urea nitrogen, serum creatinine, sodium, phosphorus, potassium, and bicarbonate were determined on the day of dialysis before SLED and within 24 h after SLED, and clinical outcomes including, acute kidney injury (AKI) recovery, in-hospital mortality, 30-day mortality, 180-day mortality, and re-admission with AKI, were evaluated. Of the 304 patients included, 69.4% were male. The majority of patients were from the Middle East (65.8%), followed by 28.6% from Asia. Four-hour SLED resulted in a significant improvement in the renal parameters. Recovery from AKI was observed in 25.4%, in-hospital mortality rate was 48.7%, while the 30- and 180-day mortality outcomes were 3.2 and 9.6%, respectively, and re-admission with AKI was observed in 16.9%. Our findings suggest that 4-h SLED significantly improved renal parameters and was associated with favorable clinical outcomes in terms of survival and AKI recovery, suggesting possible utilization of SLED shorter than 6 h in the acute settings to preserve time and manpower for procedures.https://doi.org/10.1515/med-2023-0868sustained low-efficiency dialysisacute kidney injurymortalitydialysis |
| spellingShingle | Rahhal Alaa Najim Mostafa Mahfouz Ahmed Habib Mhd Baraa Hassen Sara Seife Al-Shekh Isra’a Ahmed Ashraf Omer Toba Haneen Abbarh Shahem El Hassan Mawahib Al Yafei Sumaya Badr Amr Mahmoud Khaled Mohamed Appropriateness and clinical outcomes of short sustained low-efficiency dialysis: A national experience Open Medicine sustained low-efficiency dialysis acute kidney injury mortality dialysis |
| title | Appropriateness and clinical outcomes of short sustained low-efficiency dialysis: A national experience |
| title_full | Appropriateness and clinical outcomes of short sustained low-efficiency dialysis: A national experience |
| title_fullStr | Appropriateness and clinical outcomes of short sustained low-efficiency dialysis: A national experience |
| title_full_unstemmed | Appropriateness and clinical outcomes of short sustained low-efficiency dialysis: A national experience |
| title_short | Appropriateness and clinical outcomes of short sustained low-efficiency dialysis: A national experience |
| title_sort | appropriateness and clinical outcomes of short sustained low efficiency dialysis a national experience |
| topic | sustained low-efficiency dialysis acute kidney injury mortality dialysis |
| url | https://doi.org/10.1515/med-2023-0868 |
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