Host DNA Demethylation Induced by DNMT1 Inhibition Up-Regulates Antiviral OASL Protein during Influenza a Virus Infection

Host DNA Demethylation Induced by DNMT1 Inhibition Up-Regulates Antiviral OASL Protein during Influenza a Virus Infection

Influenza A virus (IAV) is a leading cause of human respiratory infections and poses a major public health concern. IAV replication can affect the expression of DNA methyltransferases (DNMTs), and the subsequent changes in DNA methylation regulate gene expression and may lead to abnormal gene transc...

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Bibliographic Details
Main Authors: Zhiyan Zhao, Jing Li, Ye Feng, Xiaoping Kang, Yuchang Li, Yuehong Chen, Wei Li, Wenguang Yang, Lu Zhao, Shenghai Huang, Sen Zhang, Tao Jiang
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Viruses
Subjects:
influenza A virus
DNA methyltransferase 1
miR-142-5p
PI3K/AKT
2′-5′-oligoadenylate synthetase-like protein
Online Access:https://www.mdpi.com/1999-4915/15/8/1646

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