An In Vitro Platform to Study Reversible Endothelial-to-Mesenchymal Transition

An In Vitro Platform to Study Reversible Endothelial-to-Mesenchymal Transition

Endothelial cells can acquire a mesenchymal phenotype in response to external stimuli through both mechanical and biological factors, using a process known as endothelial-to-mesenchymal (EndoMT) transition. EndoMT is characterized by the decrease in endothelial characteristics, increase in mesenchym...

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Bibliographic Details
Main Authors: Muthu Kumar Krishnamoorthi, Rajarajan A. Thandavarayan, Keith A. Youker, Arvind Bhimaraj
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
endothelial cells
L-NAME
angiotensin II
endothelial-to-mesenchymal transition
reversible EndoMT
endothelial functionality
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.912660/full

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