Risk factors for Trypanosoma cruzi infection among blood donors in Central Brazil
Characteristics and possible risk factors associated with Trypanosoma cruzi infection among blood donors were assessed within a routine screening programme in blood banks in an endemic area of Chagas disease. 6,172 voluntary blood donors were interviewed and tested for anti-T. cruzi antibodies by Ha...
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Format: | Article |
Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
1992-09-01
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Series: | Memorias do Instituto Oswaldo Cruz |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000300002 |
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author | Celina M. T. Martelli Ana Lucia S. S. Andrade Simonne A. Silva Fabio Zicker |
author_facet | Celina M. T. Martelli Ana Lucia S. S. Andrade Simonne A. Silva Fabio Zicker |
author_sort | Celina M. T. Martelli |
collection | DOAJ |
description | Characteristics and possible risk factors associated with Trypanosoma cruzi infection among blood donors were assessed within a routine screening programme in blood banks in an endemic area of Chagas disease. 6,172 voluntary blood donors were interviewed and tested for anti-T. cruzi antibodies by Haemagglutination and Complement Fixation tests in six blood banks in Goiânia-Central Brazil from October 1988 to April 1989. An overall prevalence of 2.3% for T. cruzi infection was obtained, being 3.3% for first-time blood donors, and 1.9% for regular ones (p < 0.01). Considering this seropositivity among regular blood donors, selection of candidates relying only on the history of previous donation was found to be inadequate. The risk of infection increased inversely with the degrees of education and monthly income. There was a 9.2 risk of infection (95% CI 3.8-22.6) for those who had lived more than 21 years in an endemic area compared to subjects who had never lived in rural settings, after multivariate analysis. These informations may help to review the criteria of selection of donors in order to improve quality of blood products in endemic areas. |
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format | Article |
id | doaj.art-9826b58a269a43fdac7285b25de00deb |
institution | Directory Open Access Journal |
issn | 0074-0276 1678-8060 |
language | English |
last_indexed | 2024-03-12T07:23:24Z |
publishDate | 1992-09-01 |
publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
record_format | Article |
series | Memorias do Instituto Oswaldo Cruz |
spelling | doaj.art-9826b58a269a43fdac7285b25de00deb2023-09-02T22:14:58ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80601992-09-0187333934310.1590/S0074-02761992000300002Risk factors for Trypanosoma cruzi infection among blood donors in Central BrazilCelina M. T. MartelliAna Lucia S. S. AndradeSimonne A. SilvaFabio ZickerCharacteristics and possible risk factors associated with Trypanosoma cruzi infection among blood donors were assessed within a routine screening programme in blood banks in an endemic area of Chagas disease. 6,172 voluntary blood donors were interviewed and tested for anti-T. cruzi antibodies by Haemagglutination and Complement Fixation tests in six blood banks in Goiânia-Central Brazil from October 1988 to April 1989. An overall prevalence of 2.3% for T. cruzi infection was obtained, being 3.3% for first-time blood donors, and 1.9% for regular ones (p < 0.01). Considering this seropositivity among regular blood donors, selection of candidates relying only on the history of previous donation was found to be inadequate. The risk of infection increased inversely with the degrees of education and monthly income. There was a 9.2 risk of infection (95% CI 3.8-22.6) for those who had lived more than 21 years in an endemic area compared to subjects who had never lived in rural settings, after multivariate analysis. These informations may help to review the criteria of selection of donors in order to improve quality of blood products in endemic areas.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000300002Trypanosoma cruzi infectionrisk factorsblood donors |
spellingShingle | Celina M. T. Martelli Ana Lucia S. S. Andrade Simonne A. Silva Fabio Zicker Risk factors for Trypanosoma cruzi infection among blood donors in Central Brazil Memorias do Instituto Oswaldo Cruz Trypanosoma cruzi infection risk factors blood donors |
title | Risk factors for Trypanosoma cruzi infection among blood donors in Central Brazil |
title_full | Risk factors for Trypanosoma cruzi infection among blood donors in Central Brazil |
title_fullStr | Risk factors for Trypanosoma cruzi infection among blood donors in Central Brazil |
title_full_unstemmed | Risk factors for Trypanosoma cruzi infection among blood donors in Central Brazil |
title_short | Risk factors for Trypanosoma cruzi infection among blood donors in Central Brazil |
title_sort | risk factors for trypanosoma cruzi infection among blood donors in central brazil |
topic | Trypanosoma cruzi infection risk factors blood donors |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000300002 |
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