Metalloproteinases and Their Inhibitors: Potential for the Development of New Therapeutics

Metalloproteinases and Their Inhibitors: Potential for the Development of New Therapeutics

The metalloproteinase (MP) family of zinc-dependent proteases, including matrix metalloproteinases (MMPs), a disintegrin and metalloproteases (ADAMs), and a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTSs) plays a crucial role in the extracellular matrix (ECM) remodeling and de...

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Bibliographic Details
Main Authors: Maryam Raeeszadeh-Sarmazdeh, Linh D. Do, Brianne G. Hritz
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
metalloproteinases
metzincins
matrix metalloproteinases
MMPs
a disintegrin and metalloproteases
ADAMs
Online Access:https://www.mdpi.com/2073-4409/9/5/1313

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