An East Asian Common Variant Vinculin P.Asp841His Was Associated With Sudden Unexplained Nocturnal Death Syndrome in the Chinese Han Population

An East Asian Common Variant Vinculin P.Asp841His Was Associated With Sudden Unexplained Nocturnal Death Syndrome in the Chinese Han Population

BackgroundWe have identified the cardiomyopathy‐susceptibility gene vinculin (VCL) mutation M94I may account for a sudden unexplained nocturnal death syndrome (SUNDS) case. We addressed whether VCL common variant D841H is associated with SUNDS. Methods and ResultsIn 8 of 120 SUNDS cases, we detected...

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Bibliographic Details
Main Authors: Jianding Cheng, John W. Kyle, Di Lang, Brandi Wiedmeyer, Jian Guo, Kun Yin, Lei Huang, Ravi Vaidyanathan, Terry Su, Jonathan C. Makielski
Format: Article
Language:English
Published: Wiley 2017-04-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiac sodium channel
sudden cardiac death
sudden unexplained nocturnal death syndrome
vinculin
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.116.005330

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.116.005330

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