Multiple Sevoflurane Exposures During the Neonatal Period Cause Hearing Impairment and Loss of Hair Cell Ribbon Synapses in Adult Mice

Multiple Sevoflurane Exposures During the Neonatal Period Cause Hearing Impairment and Loss of Hair Cell Ribbon Synapses in Adult Mice

ObjectivesThis study aims to investigate the effects of multiple sevoflurane exposures in neonatal mice on hearing function in the later life and explores the underlying mechanisms and protective strategies.Materials and MethodsNeonatal Kunming mice were exposed to sevoflurane for 3 days. Auditory b...

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Bibliographic Details
Main Authors:	Yufeng Li, Huiqian Yu, Xuehua Zhou, Lin Jin, Wen Li, Geng-Lin Li, Xia Shen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-07-01
Series:	Frontiers in Neuroscience
Subjects:	sevoflurane hearing impairment hair cells ribbon synapse spiral ganglion neuron nerve fiber oxidative stress
Online Access:	https://www.frontiersin.org/articles/10.3389/fnins.2022.945277/full

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