Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts
Fungal infections are a growing health care challenge. Neutrophils play a key role in defense against fungal infections. There are many effective ways for neutrophils to eliminate fungal invaders, such as phagocytosis, oxidative bursts, and the formation of extracellular traps. This process has rece...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.977493/full |
| _version_ | 1811183610825277440 |
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| author | Hua Zhong Ren-Yi Lu Yan Wang |
| author_facet | Hua Zhong Ren-Yi Lu Yan Wang |
| author_sort | Hua Zhong |
| collection | DOAJ |
| description | Fungal infections are a growing health care challenge. Neutrophils play a key role in defense against fungal infections. There are many effective ways for neutrophils to eliminate fungal invaders, such as phagocytosis, oxidative bursts, and the formation of extracellular traps. This process has received considerable attention and has made rapid progress since neutrophil extracellular traps (NETs) formation was described. Here, we describe the formation, induction, and function of NETs, as well as fungal strategies against NETs hunting. We highlight the effects of NETs on common fungal pathogens and how these pathogens survive. |
| first_indexed | 2024-04-11T09:48:49Z |
| format | Article |
| id | doaj.art-98338c6cc846471d9d81db196e17435e |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-04-11T09:48:49Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-98338c6cc846471d9d81db196e17435e2022-12-22T04:30:52ZengFrontiers Media S.A.Frontiers in Immunology1664-32242022-09-011310.3389/fimmu.2022.977493977493Neutrophil extracellular traps in fungal infections: A seesaw battle in hostsHua ZhongRen-Yi LuYan WangFungal infections are a growing health care challenge. Neutrophils play a key role in defense against fungal infections. There are many effective ways for neutrophils to eliminate fungal invaders, such as phagocytosis, oxidative bursts, and the formation of extracellular traps. This process has received considerable attention and has made rapid progress since neutrophil extracellular traps (NETs) formation was described. Here, we describe the formation, induction, and function of NETs, as well as fungal strategies against NETs hunting. We highlight the effects of NETs on common fungal pathogens and how these pathogens survive.https://www.frontiersin.org/articles/10.3389/fimmu.2022.977493/fullneutrophilneutrophil extracellular trapsfungal infectionimmunologyCandidaAspergillus |
| spellingShingle | Hua Zhong Ren-Yi Lu Yan Wang Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts Frontiers in Immunology neutrophil neutrophil extracellular traps fungal infection immunology Candida Aspergillus |
| title | Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts |
| title_full | Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts |
| title_fullStr | Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts |
| title_full_unstemmed | Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts |
| title_short | Neutrophil extracellular traps in fungal infections: A seesaw battle in hosts |
| title_sort | neutrophil extracellular traps in fungal infections a seesaw battle in hosts |
| topic | neutrophil neutrophil extracellular traps fungal infection immunology Candida Aspergillus |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2022.977493/full |
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