Descriptive registry study on outcome and complications of external ventricular drainage treatment of intraventricular haemorrhage in a Danish cohort: a study protocol
Introduction Intraventricular haemorrhage (IVH) is associated with high morbidity and mortality. External ventricular drainage (EVD) has been shown to decrease mortality. Although EVD is widely used, outcome and complication rates in EVD-treated patients with IVH are not fully elucidated. This study...
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| Format: | Article |
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BMJ Publishing Group
2024-01-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/14/1/e075997.full |
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| author | Mads Rasmussen Claus Ziegler Simonsen Chenghao Gu Mette Haldrup Stig Dyrskog Mads Hjortdal Grønhøj Frantz Rom Poulsen Thor Busse Joakim Wismann Birgit Debrabant Anders Rosendal Korshoej |
| author_facet | Mads Rasmussen Claus Ziegler Simonsen Chenghao Gu Mette Haldrup Stig Dyrskog Mads Hjortdal Grønhøj Frantz Rom Poulsen Thor Busse Joakim Wismann Birgit Debrabant Anders Rosendal Korshoej |
| author_sort | Mads Rasmussen |
| collection | DOAJ |
| description | Introduction Intraventricular haemorrhage (IVH) is associated with high morbidity and mortality. External ventricular drainage (EVD) has been shown to decrease mortality. Although EVD is widely used, outcome and complication rates in EVD-treated patients with IVH are not fully elucidated. This study aims to describe EVD complication rates and outcomes in patients with primary and secondary IVH at two university hospitals in Denmark. The study will provide a historical reference of relevant endpoints for use in future clinical trials involving patients with IVH.Methods and analysis This descriptive, multicentre registry study included adult patients (age 18+) with primary or secondary IVH and treated with at least one EVD between 2017 and 2021 at Aarhus University Hospital or Odense University Hospital. Patients are identified using the Danish National Patient Register. Data are collected and recorded from patient medical records. Relevant descriptive statistics and correlation analyses will be applied.Ethics and dissemination Ethical approval and authorisation to access, store and analyse data have been obtained (Central Denmark Region Committee on Health Research Ethics). The research lead will present the results of the study. Data will be reported according to the Strengthening the Reporting of Observational Studies in Epidemiology and results submitted for publication in peer-reviewed journals. |
| first_indexed | 2024-03-07T21:46:34Z |
| format | Article |
| id | doaj.art-98354411548c4ab3a5a8e166f65278aa |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-03-07T21:46:34Z |
| publishDate | 2024-01-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj.art-98354411548c4ab3a5a8e166f65278aa2024-02-25T11:45:09ZengBMJ Publishing GroupBMJ Open2044-60552024-01-0114110.1136/bmjopen-2023-075997Descriptive registry study on outcome and complications of external ventricular drainage treatment of intraventricular haemorrhage in a Danish cohort: a study protocolMads Rasmussen0Claus Ziegler Simonsen1Chenghao Gu2Mette Haldrup3Stig Dyrskog4Mads Hjortdal Grønhøj5Frantz Rom Poulsen6Thor Busse7Joakim Wismann8Birgit Debrabant9Anders Rosendal Korshoej10Department of Anesthesiology, Aarhus University Hospital, Aarhus, DenmarkDepartment of Clinical Medicine, Aarhus University, Aarhus, DenmarkDepartment of Neurosurgery, Aarhus University Hospital, Aarhus, DenmarkDepartment of Neurosurgery, Aarhus University Hospital, Aarhus, DenmarkDepartment of Intensive Care, Aarhus University Hospital, Aarhus, DenmarkClinical Institute, University of Southern Denmark, Odense, DenmarkDepartment of Neurosurgery, Odense University Hospital, Odense, DenmarkDepartment of Neurosurgery, Odense University Hospital, Odense, DenmarkDepartment of Neurosurgery, Odense University Hospital, Odense, DenmarkDepartment of Mathematics and Computer Science, University of Southern Denmark, Odense, DenmarkDepartment of Neurosurgery, Aarhus University Hospital, Aarhus, DenmarkIntroduction Intraventricular haemorrhage (IVH) is associated with high morbidity and mortality. External ventricular drainage (EVD) has been shown to decrease mortality. Although EVD is widely used, outcome and complication rates in EVD-treated patients with IVH are not fully elucidated. This study aims to describe EVD complication rates and outcomes in patients with primary and secondary IVH at two university hospitals in Denmark. The study will provide a historical reference of relevant endpoints for use in future clinical trials involving patients with IVH.Methods and analysis This descriptive, multicentre registry study included adult patients (age 18+) with primary or secondary IVH and treated with at least one EVD between 2017 and 2021 at Aarhus University Hospital or Odense University Hospital. Patients are identified using the Danish National Patient Register. Data are collected and recorded from patient medical records. Relevant descriptive statistics and correlation analyses will be applied.Ethics and dissemination Ethical approval and authorisation to access, store and analyse data have been obtained (Central Denmark Region Committee on Health Research Ethics). The research lead will present the results of the study. Data will be reported according to the Strengthening the Reporting of Observational Studies in Epidemiology and results submitted for publication in peer-reviewed journals.https://bmjopen.bmj.com/content/14/1/e075997.full |
| spellingShingle | Mads Rasmussen Claus Ziegler Simonsen Chenghao Gu Mette Haldrup Stig Dyrskog Mads Hjortdal Grønhøj Frantz Rom Poulsen Thor Busse Joakim Wismann Birgit Debrabant Anders Rosendal Korshoej Descriptive registry study on outcome and complications of external ventricular drainage treatment of intraventricular haemorrhage in a Danish cohort: a study protocol BMJ Open |
| title | Descriptive registry study on outcome and complications of external ventricular drainage treatment of intraventricular haemorrhage in a Danish cohort: a study protocol |
| title_full | Descriptive registry study on outcome and complications of external ventricular drainage treatment of intraventricular haemorrhage in a Danish cohort: a study protocol |
| title_fullStr | Descriptive registry study on outcome and complications of external ventricular drainage treatment of intraventricular haemorrhage in a Danish cohort: a study protocol |
| title_full_unstemmed | Descriptive registry study on outcome and complications of external ventricular drainage treatment of intraventricular haemorrhage in a Danish cohort: a study protocol |
| title_short | Descriptive registry study on outcome and complications of external ventricular drainage treatment of intraventricular haemorrhage in a Danish cohort: a study protocol |
| title_sort | descriptive registry study on outcome and complications of external ventricular drainage treatment of intraventricular haemorrhage in a danish cohort a study protocol |
| url | https://bmjopen.bmj.com/content/14/1/e075997.full |
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