Glucocorticoid Receptor Polymorphism A3669G Is Associated with Airflow Obstruction in Mild-to-Severe Asthma

Glucocorticoid Receptor Polymorphism A3669G Is Associated with Airflow Obstruction in Mild-to-Severe Asthma

Background: Glucocorticoids (GCs) represent the mainstay therapy for asthmatics. A subset of severe asthmatics fails to respond to steroid-based therapies, leading to important healthcare costs. Single nucleotide polymorphisms (SNPs) of glucocorticoid receptor genes were associated with a response t...

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Bibliographic Details
Main Authors: Barbara Mognetti, Daniela Francesca Giachino, Francesca Bertolini, Vitina Carriero, Andrea Elio Sprio, Fabio Luigi Massimo Ricciardolo
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Applied Sciences
Subjects:
asthma
glucocorticoid receptor gene
airflow obstruction
air trapping
SNP
Online Access:https://www.mdpi.com/2076-3417/13/13/7450

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