Monogenic Adult-Onset Inborn Errors of Immunity

Monogenic Adult-Onset Inborn Errors of Immunity

Inborn errors of immunity (IEI) are a heterogenous group of disorders driven by genetic defects that functionally impact the development and/or function of the innate and/or adaptive immune system. The majority of these disorders are thought to have polygenic background. However, the use of next-gen...

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Bibliographic Details
Main Authors: Frederik Staels, Tom Collignon, Albrecht Betrains, Margaux Gerbaux, Mathijs Willemsen, Stephanie Humblet-Baron, Adrian Liston, Steven Vanderschueren, Rik Schrijvers
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
primary immunodeficiency
genetics
adult-onset
monogenic
mutation
inborn errors of immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.753978/full

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