Dissociation between AKAP3 and PKARII promotes AKAP3 degradation in sperm capacitation.

Dissociation between AKAP3 and PKARII promotes AKAP3 degradation in sperm capacitation.

Ejaculated spermatozoa must undergo a series of biochemical modifications called capacitation, prior to fertilization. Protein-kinase A (PKA) mediates sperm capacitation, although its regulation is not fully understood. Sperm contain several A-kinase anchoring proteins (AKAPs), which are scaffold pr...

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Bibliographic Details
Main Authors: Pnina Hillman, Debby Ickowicz, Ruth Vizel, Haim Breitbart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3720880?pdf=render

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