Are changes in olanzapine-induced liver enzyme levels associated with GSTT1, GSTM1, GSTP1, and OGG1 gene polymorphisms?

Are changes in olanzapine-induced liver enzyme levels associated with GSTT1, GSTM1, GSTP1, and OGG1 gene polymorphisms?

Olanzapine treatment sometimes produces transient liver biochemistry abnormalities, and such drug-induced liver injuries are mainly monitored by measuring blood levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST), whereas alpha-glutathione-S-transferase (α-GST) is not routi...

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Bibliographic Details
Main Authors: Elkama Aylin, İlik Nazlıcan, Ak Mehmet, Karahalil Bensu
Format: Article
Language:English
Published: Sciendo 2024-03-01
Series:Arhiv za Higijenu Rada i Toksikologiju
Subjects:
α-gst
alt
ast
drug-induced liver injury
mental disorders
psychotropic drugs
mentalni poremećaji
lijekom prouzročeno oštećenje jetre
psihotropni lijekovi
Online Access:https://doi.org/10.2478/aiht-2024-75-3770

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