Extração de bifenilas policloradas de amostras de leite materno: otimização univariada versus planejamento experimental Extraction of polychlorinated biphenyls in breast milk samples: univariated optimization versus experimental design
<abstract language="eng">The convenience of the multivariate optimization of SPME procedures through ANOVA calculated using Doehlert designs has been demonstrated for twelve PCBs in the complex matrix of milk. For this study, the main parameters of the extraction were selected and va...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Química
2013-01-01
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| Series: | Química Nova |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422013000300018 |
| _version_ | 1819038953234235392 |
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| author | Cláudia Hoffmann Kowalski Fabio Augusto Helena Teixeira Godoy |
| author_facet | Cláudia Hoffmann Kowalski Fabio Augusto Helena Teixeira Godoy |
| author_sort | Cláudia Hoffmann Kowalski |
| collection | DOAJ |
| description | <abstract language="eng">The convenience of the multivariate optimization of SPME procedures through ANOVA calculated using Doehlert designs has been demonstrated for twelve PCBs in the complex matrix of milk. For this study, the main parameters of the extraction were selected and valued through univariate and multivariate optimization. In addition, the analysis of variance allowed identification of the statistically significant variables in this model: high temperature (95 ºC) and ionic strength (36% m/v) proved significant for all the PCBs while intermediate time (70 min) and low methanol concentration (5% v/v) also contributed to the extraction of the majority of these PCBs. |
| first_indexed | 2024-12-21T08:45:30Z |
| format | Article |
| id | doaj.art-9852cb58b5b74b53af66cb82ad970cd5 |
| institution | Directory Open Access Journal |
| issn | 0100-4042 1678-7064 |
| language | English |
| last_indexed | 2024-12-21T08:45:30Z |
| publishDate | 2013-01-01 |
| publisher | Sociedade Brasileira de Química |
| record_format | Article |
| series | Química Nova |
| spelling | doaj.art-9852cb58b5b74b53af66cb82ad970cd52022-12-21T19:09:50ZengSociedade Brasileira de QuímicaQuímica Nova0100-40421678-70642013-01-01363468473Extração de bifenilas policloradas de amostras de leite materno: otimização univariada versus planejamento experimental Extraction of polychlorinated biphenyls in breast milk samples: univariated optimization versus experimental designCláudia Hoffmann KowalskiFabio AugustoHelena Teixeira Godoy<abstract language="eng">The convenience of the multivariate optimization of SPME procedures through ANOVA calculated using Doehlert designs has been demonstrated for twelve PCBs in the complex matrix of milk. For this study, the main parameters of the extraction were selected and valued through univariate and multivariate optimization. In addition, the analysis of variance allowed identification of the statistically significant variables in this model: high temperature (95 ºC) and ionic strength (36% m/v) proved significant for all the PCBs while intermediate time (70 min) and low methanol concentration (5% v/v) also contributed to the extraction of the majority of these PCBs.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422013000300018PCBsSPMEDoehlert design |
| spellingShingle | Cláudia Hoffmann Kowalski Fabio Augusto Helena Teixeira Godoy Extração de bifenilas policloradas de amostras de leite materno: otimização univariada versus planejamento experimental Extraction of polychlorinated biphenyls in breast milk samples: univariated optimization versus experimental design Química Nova PCBs SPME Doehlert design |
| title | Extração de bifenilas policloradas de amostras de leite materno: otimização univariada versus planejamento experimental Extraction of polychlorinated biphenyls in breast milk samples: univariated optimization versus experimental design |
| title_full | Extração de bifenilas policloradas de amostras de leite materno: otimização univariada versus planejamento experimental Extraction of polychlorinated biphenyls in breast milk samples: univariated optimization versus experimental design |
| title_fullStr | Extração de bifenilas policloradas de amostras de leite materno: otimização univariada versus planejamento experimental Extraction of polychlorinated biphenyls in breast milk samples: univariated optimization versus experimental design |
| title_full_unstemmed | Extração de bifenilas policloradas de amostras de leite materno: otimização univariada versus planejamento experimental Extraction of polychlorinated biphenyls in breast milk samples: univariated optimization versus experimental design |
| title_short | Extração de bifenilas policloradas de amostras de leite materno: otimização univariada versus planejamento experimental Extraction of polychlorinated biphenyls in breast milk samples: univariated optimization versus experimental design |
| title_sort | extracao de bifenilas policloradas de amostras de leite materno otimizacao univariada versus planejamento experimental extraction of polychlorinated biphenyls in breast milk samples univariated optimization versus experimental design |
| topic | PCBs SPME Doehlert design |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422013000300018 |
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