The Impact of Epitranscriptomics on Antiviral Innate Immunity

Epitranscriptomics, i.e., chemical modifications of RNA molecules, has proven to be a new layer of modulation and regulation of protein expression, asking for the revisiting of some aspects of cellular biology. At the virological level, epitranscriptomics can thus directly impact the viral life cycl...

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Bibliographic Details
Main Authors: Beril Mersinoglu, Sara Cristinelli, Angela Ciuffi
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/8/1666
Description
Summary:Epitranscriptomics, i.e., chemical modifications of RNA molecules, has proven to be a new layer of modulation and regulation of protein expression, asking for the revisiting of some aspects of cellular biology. At the virological level, epitranscriptomics can thus directly impact the viral life cycle itself, acting on viral or cellular proteins promoting replication, or impacting the innate antiviral response of the host cell, the latter being the focus of the present review.
ISSN:1999-4915