The Impact of Epitranscriptomics on Antiviral Innate Immunity
Epitranscriptomics, i.e., chemical modifications of RNA molecules, has proven to be a new layer of modulation and regulation of protein expression, asking for the revisiting of some aspects of cellular biology. At the virological level, epitranscriptomics can thus directly impact the viral life cycl...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-07-01
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| Series: | Viruses |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4915/14/8/1666 |
| _version_ | 1797407516095676416 |
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| author | Beril Mersinoglu Sara Cristinelli Angela Ciuffi |
| author_facet | Beril Mersinoglu Sara Cristinelli Angela Ciuffi |
| author_sort | Beril Mersinoglu |
| collection | DOAJ |
| description | Epitranscriptomics, i.e., chemical modifications of RNA molecules, has proven to be a new layer of modulation and regulation of protein expression, asking for the revisiting of some aspects of cellular biology. At the virological level, epitranscriptomics can thus directly impact the viral life cycle itself, acting on viral or cellular proteins promoting replication, or impacting the innate antiviral response of the host cell, the latter being the focus of the present review. |
| first_indexed | 2024-03-09T03:42:37Z |
| format | Article |
| id | doaj.art-98533e20e87d497081b5e355209aaeb4 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-09T03:42:37Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-98533e20e87d497081b5e355209aaeb42023-12-03T14:38:57ZengMDPI AGViruses1999-49152022-07-01148166610.3390/v14081666The Impact of Epitranscriptomics on Antiviral Innate ImmunityBeril Mersinoglu0Sara Cristinelli1Angela Ciuffi2Institute of Microbiology, Lausanne University Hospital, University of Lausanne, CH-1011 Lausanne, SwitzerlandInstitute of Microbiology, Lausanne University Hospital, University of Lausanne, CH-1011 Lausanne, SwitzerlandInstitute of Microbiology, Lausanne University Hospital, University of Lausanne, CH-1011 Lausanne, SwitzerlandEpitranscriptomics, i.e., chemical modifications of RNA molecules, has proven to be a new layer of modulation and regulation of protein expression, asking for the revisiting of some aspects of cellular biology. At the virological level, epitranscriptomics can thus directly impact the viral life cycle itself, acting on viral or cellular proteins promoting replication, or impacting the innate antiviral response of the host cell, the latter being the focus of the present review.https://www.mdpi.com/1999-4915/14/8/1666epitranscriptomicsantiviral immunityRIG-I sensingIFN-I responseviral infection |
| spellingShingle | Beril Mersinoglu Sara Cristinelli Angela Ciuffi The Impact of Epitranscriptomics on Antiviral Innate Immunity Viruses epitranscriptomics antiviral immunity RIG-I sensing IFN-I response viral infection |
| title | The Impact of Epitranscriptomics on Antiviral Innate Immunity |
| title_full | The Impact of Epitranscriptomics on Antiviral Innate Immunity |
| title_fullStr | The Impact of Epitranscriptomics on Antiviral Innate Immunity |
| title_full_unstemmed | The Impact of Epitranscriptomics on Antiviral Innate Immunity |
| title_short | The Impact of Epitranscriptomics on Antiviral Innate Immunity |
| title_sort | impact of epitranscriptomics on antiviral innate immunity |
| topic | epitranscriptomics antiviral immunity RIG-I sensing IFN-I response viral infection |
| url | https://www.mdpi.com/1999-4915/14/8/1666 |
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